[HTML][HTML] Traditional Chinese medicine combined with pulmonary drug delivery system and idiopathic pulmonary fibrosis: rationale and therapeutic potential
Y Zhang, P Lu, H Qin, Y Zhang, X Sun, X Song… - Biomedicine & …, 2021 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a progressive pulmonary interstitial inflammatory
disease of unknown etiology, and is also a sequela in severe patients with the Coronavirus …
disease of unknown etiology, and is also a sequela in severe patients with the Coronavirus …
Physical stability of dry powder inhaler formulations
ABSTRACT Introduction: Dry powder inhalers (DPIs) are popular for pulmonary drug
delivery. Various techniques have been employed to produce inhalation drug particles and …
delivery. Various techniques have been employed to produce inhalation drug particles and …
Leucine as an excipient in spray dried powder for inhalation
Leucine is a promising excipient with several applications in the development of inhalable
spray-dried powder of high-and low-dose drugs. The addition of leucine has exhibited …
spray-dried powder of high-and low-dose drugs. The addition of leucine has exhibited …
[HTML][HTML] Designing enhanced spray dried particles for inhalation: A review of the impact of excipients and processing parameters on particle properties
Spray drying is a constructive single-step manufacturing technique used to produce dry
powder. Spray drying plays a remarkable role in producing inhalable powder formulations …
powder. Spray drying plays a remarkable role in producing inhalable powder formulations …
Dry powder pharmaceutical biologics for inhalation therapy
Therapeutic biologics such as genes, peptides, proteins, virus and cells provide clinical
benefits and are becoming increasingly important tools in respiratory medicine. Pulmonary …
benefits and are becoming increasingly important tools in respiratory medicine. Pulmonary …
Engineering the right formulation for enhanced drug delivery
Dry powder inhalers (DPIs) can be used with a wide range of drugs such as small molecules
and biologics and offer several advantages for inhaled therapy. Early DPI products were …
and biologics and offer several advantages for inhaled therapy. Early DPI products were …
[HTML][HTML] Leucine improves the aerosol performance of dry powder inhaler formulations of siRNA-loaded nanoparticles
Thermostable dry powder inhaler (DPI) formulations with high aerosol performance are
attractive inhalable solid dosage forms for local treatment of inflammatory lung diseases. We …
attractive inhalable solid dosage forms for local treatment of inflammatory lung diseases. We …
A comprehensive overview of dry powder inhalers for pulmonary drug delivery: Challenges, advances, optimization techniques, and applications
Dry powder inhaler (DPI) is an attractive dosage form for local and systemic pulmonary drug
delivery. However, designing DPIs with adequate physicochemical properties is …
delivery. However, designing DPIs with adequate physicochemical properties is …
Influence of excipients on physical and aerosolization stability of spray dried high-dose powder formulations for inhalation
The aim of this study is to investigate the influence of excipients on physical and
aerosolization stability of spray dried Ciprofloxacin dry powder inhaler formulations. The …
aerosolization stability of spray dried Ciprofloxacin dry powder inhaler formulations. The …
Production of highly stable spray dried phage formulations for treatment of Pseudomonas aeruginosa lung infection
RY Chang, J Wong, A Mathai, S Morales… - European Journal of …, 2017 - Elsevier
The potential of bacteriophage therapy for the treatment of pulmonary infections caused by
antibiotic-resistant bacteria has been well recognised. The purpose of this study was to …
antibiotic-resistant bacteria has been well recognised. The purpose of this study was to …