There is an increasing role for biological markers (biomarkers) in the understanding and
diagnosis of neurodegenerative disorders. The application of imaging biomarkers …

Alzheimer's disease (AD) is a neurodegenerative disorder of the elderly. As the prevalence
of AD rises in the 21st century, there is an urgent need for the development of effective …

Brain functional networks have been traditionally studied considering only interactions
between pairs of regions, neglecting the richer information encoded in higher orders of …

Objective To determine the in vivo cortical spreading pattern of tau and amyloid and to
establish positron emission tomography (PET) image‐based tau staging in the Alzheimer …

Many studies of the human brain have explored the relationship between cortical thickness
and cognition, phenotype, or disease. Due to the subjectivity and time requirements in …

Based on the recent literature and collective experience, an international consortium
developed revised guidelines for the diagnosis of behavioural variant frontotemporal …

Effective and accurate diagnosis of Alzheimer's disease (AD), as well as its prodromal stage
(ie, mild cognitive impairment (MCI)), has attracted more and more attention recently. So far …

Introduction Deteriorating brain glucose metabolism precedes the clinical onset of
Alzheimer's disease (AD) and appears to contribute to its etiology. Ketone bodies, mainly β …

The presymptomatic phase of Alzheimer disease (AD) starts with the deposition of amyloid-β
in the cortex and begins a decade or more before the emergence of cognitive decline. The …

The structure of the brain is constantly changing from birth throughout the lifetime, meaning
that normal aging, free from dementia, is associated with structural brain changes. This …