The basal ganglia (BG) and the cerebellum historically have been relegated to a functional
role in producing or modulating motor output. Recent research, however, has emphasized …

Deep-Brain Stimulation for Parkinson's Disease | New England Journal of Medicine Skip to main
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Chronic dopamine depletion in Parkinson's disease leads to progressive motor and
cognitive impairment, which is associated with the emergence of characteristic patterns of …

Deep brain stimulation of different targets has been shown to drastically improve symptoms
of a variety of neurological conditions. However, the occurrence of disabling side effects may …

Brain stimulation, a therapy increasingly used for neurological and psychiatric disease,
traditionally is divided into invasive approaches, such as deep brain stimulation (DBS), and …

The ability to stop already-initiated actions is a key cognitive control ability. Recent work on
human action-stop** has been dominated by two controversial debates. First, the …

Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized
by deficits in social communication, social interaction, and repetitive restricted behaviors …

A monosynaptic projection from the cortex to the subthalamic nucleus is thought to have an
important role in basal ganglia function and in the mechanism of therapeutic subthalamic …

Advances in molecular and structural and functional neuroimaging are rapidly expanding
the complexity of neurobiological understanding of Parkinson's disease (PD). This review …

Deep brain stimulation of the subthalamic nucleus is an established treatment for the motor
symptoms of Parkinson's disease. Given the frequent occurrence of stimulation-induced …