Amino acid metabolism in immune cells: essential regulators of the effector functions, and promising opportunities to enhance cancer immunotherapy

L Yang, Z Chu, M Liu, Q Zou, J Li, Q Liu… - Journal of hematology & …, 2023‏ - Springer
Amino acids are basic nutrients for immune cells during organ development, tissue
homeostasis, and the immune response. Regarding metabolic reprogramming in the tumor …

Signaling pathways in rheumatoid arthritis: implications for targeted therapy

Q Ding, W Hu, R Wang, Q Yang, M Zhu, M Li… - Signal transduction and …, 2023‏ - nature.com
Rheumatoid arthritis (RA) is an incurable systemic autoimmune disease. Disease
progression leads to joint deformity and associated loss of function, which significantly …

Macrophage plasticity: signaling pathways, tissue repair, and regeneration

L Yan, J Wang, X Cai, YC Liou, HM Shen, J Hao… - MedComm, 2024‏ - Wiley Online Library
Macrophages are versatile immune cells with remarkable plasticity, enabling them to adapt
to diverse tissue microenvironments and perform various functions. Traditionally categorized …

[HTML][HTML] Engineered neutrophil apoptotic bodies ameliorate myocardial infarction by promoting macrophage efferocytosis and inflammation resolution

L Bao, G Dou, R Tian, Y Lv, F Ding, S Liu, R Zhao… - Bioactive materials, 2022‏ - Elsevier
Inflammatory response plays a critical role in myocardial infarction (MI) repair. The
neutrophil apoptosis and subsequent macrophage ingestion can result in inflammation …

L-arginine metabolism inhibits arthritis and inflammatory bone loss

S Cao, Y Li, R Song, X Meng, M Fuchs, C Liang… - Annals of the rheumatic …, 2024‏ - Elsevier
Objectives To investigate the effect of the L-arginine metabolism on arthritis and
inflammation-mediated bone loss. Methods L-arginine was applied to three arthritis models …