We present a comprehensive overview of the hierarchical network of intracellular processes
revolving around central nitrogen metabolism in Escherichia coli. The hierarchy intertwines …

After about ten years of research renaissance in metabolism, the present challenge is to
understand how metabolic fluxes are controlled by a complex interplay of overlap** …

Living organisms persist by virtue of complex interactions among many components
organized into dynamic, environment-responsive networks that span multiple scales and …

The liver is the central metabolic organ in human physiology, with functions that are
fundamentally important to the detoxification of xenobiotics (drugs), the maintenance of …

This review describes the recent experimental data on the importance of the VDAC–
cytoskeleton interactions in determining the mechanisms of energy and metabolite transfer …

Metabolic pathways can be engineered to maximize the synthesis of various products of
interest. With the advent of computational systems biology, this endeavour is usually carried …

Systems Biology has a mission that puts it at odds with traditional paradigms of physics and
molecular biology, such as the simplicity requested by Occam's razor and minimum …

A molecularly imprinted polymer-based pencil graphite electrode (MIP PGE) sensor,
modified with gold nanoparticles, was utilized for the detection of dopamine in the presence …

Mitochondria–cytoskeleton interactions were analyzed in adult rat cardiomyocytes and in
cancerous non-beating HL-1 cells of cardiac phenotype. We show that in adult …

Much of the search for the “magic cancer bullet” or “block buster” has followed the
expectation of a single gene or protein as “the rate-limiting step” for tumor persistence …