Mitophagy: an emerging role in aging and age-associated diseases

G Chen, G Kroemer, O Kepp - Frontiers in cell and developmental …, 2020 - frontiersin.org
Mitochondrial dysfunction constitutes one of the hallmarks of aging and is characterized by
irregular mitochondrial morphology, insufficient ATP production, accumulation of …

[HTML][HTML] Protective role of melatonin and its metabolites in skin aging

G Bocheva, RM Slominski, Z Janjetovic, TK Kim… - International journal of …, 2022 - mdpi.com
The skin, being the largest organ in the human body, is exposed to the environment and
suffers from both intrinsic and extrinsic aging factors. The skin aging process is …

Multidisciplinary haematology as prognostic device in environmental and xenobiotic stress-induced response in fish

MA Burgos-Aceves, L Lionetti, C Faggio - Science of the total environment, 2019 - Elsevier
The variations of haematological parameters hematocrit, hemoglobin concentration,
leukocyte and erythrocyte count have been used as pollution and physiological indicators of …

Mitochondria and reactive oxygen species in aging and age-related diseases

C Giorgi, S Marchi, ICM Simoes, Z Ren… - International review of …, 2018 - Elsevier
Aging has been linked to several degenerative processes that, through the accumulation of
molecular and cellular damage, can progressively lead to cell dysfunction and organ failure …

Obesity may accelerate the aging process

V Salvestrini, C Sell, A Lorenzini - Frontiers in endocrinology, 2019 - frontiersin.org
Lines of evidence from several studies have shown that increases in life expectancy are now
accompanied by increased disability rate. The expanded lifespan of the aging population …

Recent advances in health benefits and bioavailability of dietary astaxanthin and its isomers

X Liu, J **e, L Zhou, J Zhang, Z Chen, J **ao, Y Cao… - Food chemistry, 2023 - Elsevier
Astaxanthin, a xanthophyll carotenoid, has attracted considerable attention owing to its
unique molecular structure and excellent antioxidant properties. Due to its structural …

Aging-Oxidative stress, antioxidants and computational modeling

F Hussain, HUR Kayani - Heliyon, 2020 - cell.com
Aging is a degenerative, biological, time-dependent, universally conserved process thus
designed as one of the highest known risk factors for morbidity and mortality. Every …

[HTML][HTML] Inhibitory effect of astaxanthin on oxidative stress-induced mitochondrial dysfunction-a mini-review

SH Kim, H Kim - Nutrients, 2018 - mdpi.com
Oxidative stress is a major contributor to the pathogenesis of various human diseases as
well as to the aging process. Mitochondria, as the center of cellular metabolism and major …

Pathology and mechanisms of cochlear aging

EM Keithley - Journal of Neuroscience Research, 2020 - Wiley Online Library
Presbycusis, or age‐related hearing loss (ARHL), occurs in most mammals with variations in
the age of onset, rate of decline, and magnitude of degeneration in the central nervous …

Hypoxia and aging

EJ Yeo - Experimental & molecular medicine, 2019 - nature.com
Eukaryotic cells require sufficient oxygen (O2) for biological activity and survival. When the
oxygen demand exceeds its supply, the oxygen levels in local tissues or the whole body …