The emergence of Zika virus and its new clinical syndromes
TC Pierson, MS Diamond - Nature, 2018 - nature.com
Zika virus (ZIKV) is a mosquito-transmitted flavivirus that has emerged as a global health
threat because of its potential to generate explosive epidemics and ability to cause …
threat because of its potential to generate explosive epidemics and ability to cause …
Biochemistry and molecular biology of flaviviruses
Flaviviruses, such as dengue, Japanese encephalitis, tick-borne encephalitis, West Nile,
yellow fever, and Zika viruses, are critically important human pathogens that sicken a …
yellow fever, and Zika viruses, are critically important human pathogens that sicken a …
Immune response to dengue and Zika
A Elong Ngono, S Shresta - Annual review of immunology, 2018 - annualreviews.org
Flaviviruses such as dengue (DENV), yellow fever (YFV), West Nile (WNV), and Zika (ZIKV)
are human pathogens of global significance. In particular, DENV causes the most prevalent …
are human pathogens of global significance. In particular, DENV causes the most prevalent …
Evidence and possible mechanisms of rare maternal-fetal transmission of SARS-CoV-2
While SARS-CoV-2 infection has spread rapidly worldwide, data remains scarce about the
natural history of infection in pregnant women and the risk of mother-to-fetal transmission …
natural history of infection in pregnant women and the risk of mother-to-fetal transmission …
Nonhuman primate models of human viral infections
Humans have a close phylogenetic relationship with nonhuman primates (NHPs) and share
many physiological parallels, such as highly similar immune systems, with them. Importantly …
many physiological parallels, such as highly similar immune systems, with them. Importantly …
Zika virus infection in pregnant rhesus macaques causes placental dysfunction and immunopathology
AJ Hirsch, VHJ Roberts, PL Grigsby, N Haese… - Nature …, 2018 - nature.com
Zika virus (ZIKV) infection during pregnancy leads to an increased risk of fetal growth
restriction and fetal central nervous system malformations, which are outcomes broadly …
restriction and fetal central nervous system malformations, which are outcomes broadly …
The evolution of Zika virus from Asia to the Americas
Zika virus (ZIKV) was once considered an obscure member of the large and diverse family of
mosquito-borne flaviviruses, and human infections with ZIKV were thought to be sporadic …
mosquito-borne flaviviruses, and human infections with ZIKV were thought to be sporadic …
Zika virus vaccines
The recent epidemic of Zika virus (ZIKV) in the Americas has revealed the devastating
consequences of ZIKV infection, particularly in pregnant women. Congenital Zika syndrome …
consequences of ZIKV infection, particularly in pregnant women. Congenital Zika syndrome …
Immunobiology of acute chorioamnionitis
Acute chorioamnionitis is characterized by neutrophilic infiltration and inflammation at the
maternal fetal interface. It is a relatively common complication of pregnancy and can have …
maternal fetal interface. It is a relatively common complication of pregnancy and can have …
A human bi-specific antibody against Zika virus with high therapeutic potential
Zika virus (ZIKV), a mosquito-borne flavivirus, causes devastating congenital birth defects.
We isolated a human monoclonal antibody (mAb), ZKA190, that potently cross-neutralizes …
We isolated a human monoclonal antibody (mAb), ZKA190, that potently cross-neutralizes …