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Naphthalene, a versatile platform in medicinal chemistry: Sky-high perspective
Naphthalene, a cytotoxic moiety, is an extensively explored aromatic conjugated system with
applications in various pathophysiological conditions viz. anticancer, antimicrobial, anti …
applications in various pathophysiological conditions viz. anticancer, antimicrobial, anti …
Convenient Synthesis and Anticancer Activity of Methyl 2-[3-(3-Phenyl-quinoxalin-2-ylsulfanyl)propanamido]alkanoates and N-Alkyl 3-((3-Phenyl-quinoxalin-2-yl) …
A series of methyl 2-[3-(3-phenyl-quinoxalin-2-ylsulfanyl) propanamido] alkanoates and their
corresponding hydrazides and N-alkyl 3-((3-phenylquinoxalin-2-yl) sulfanyl) propanamides …
corresponding hydrazides and N-alkyl 3-((3-phenylquinoxalin-2-yl) sulfanyl) propanamides …
Amino acid derivatives, part 4: Synthesis and anti‐HIV activity of new naphthalene derivatives
A new series of 2‐(naphthalen‐2‐yloxy)‐N‐[(aryl‐5‐thioxo‐4, 5‐dihydro‐1H‐1, 2, 4‐triazol‐
3‐yl) methyl] acetamides 5a–f was synthesized from naphthalene‐derived glycine derivative …
3‐yl) methyl] acetamides 5a–f was synthesized from naphthalene‐derived glycine derivative …
The synthesis and antiproliferative activity of new N-allyl quinoxalinecarboxamides and their O-regioisomers
We have designed a series of quinoxalinepeptidomimetic derivatives based on our
previously reported scaffold in an attempt to find a promising lead compound …
previously reported scaffold in an attempt to find a promising lead compound …
Convenient Synthesis of N-Alkyl-2-(3-phenyl-quinoxalin-2-ylsulfanyl)acetamides and Methyl-2-[2-(3-phenyl-quinoxalin-2-ylsulfanyl)acetylamino]alkanoates
A series of 27 new quinoxaline derivatives (N-alkyl-[2-(3-phenyl-quinoxalin-2-ylsulfanyl)]
acetamides, methyl-2-[2-(3-phenylquinoxalin-2-ylsulfanyl)-acetylamino] alkanoates, and …
acetamides, methyl-2-[2-(3-phenylquinoxalin-2-ylsulfanyl)-acetylamino] alkanoates, and …
Synthesis and antiviral evaluation of new N‐acylhydrazones containing glycine residue
B Tian, M He, Z Tan, S Tang, I Hewlett… - Chemical biology & …, 2011 - Wiley Online Library
N‐acylhydrazones containing glycine residue 3a–j and 8a–h were synthesized as HIV‐1
capsid protein assembly inhibitors. The structures of the novel N‐acylhydrazone derivatives …
capsid protein assembly inhibitors. The structures of the novel N‐acylhydrazone derivatives …
Synthesis and anti-HIV activity of new benzimidazole, benzothiazole and carbohyrazide derivatives of the anti-inflammatory drug indomethacin
NA Al-Masoudi, NNA Jafar, LJ Abbas… - … für Naturforschung B, 2011 - degruyter.com
There is an urgent need for the design and development of new and safer drugs for the
treatment of HIV infection, active against the currently resistant viral strains. New derivatives …
treatment of HIV infection, active against the currently resistant viral strains. New derivatives …
Synthesis and Anti proliferative Activity of New N‐Pentylquinoxaline carboxamides and Their O‐Regioisomer
We have designed a series of quinoxalinepeptidomimetic derivatives based on our previous
reported scaffold in attempt to find a promising lead compound. Quinoxaline derivatives; N …
reported scaffold in attempt to find a promising lead compound. Quinoxaline derivatives; N …
Efficient synthesis of 1‐substituted‐4‐phenyl‐1, 4‐dihydro‐5H‐tetrazole‐5‐thione and (1‐phenyl‐1H‐tetrazol‐5‐yl)thioacetyl derivatives
W Fathalla, IAI Ali - … Chemistry: An International Journal of Main …, 2007 - Wiley Online Library
A new and convenient synthesis of a variety of N‐and S‐substituted tetrazoles has been
developed via azide and Mannich reaction methods. Compounds were characterized by …
developed via azide and Mannich reaction methods. Compounds were characterized by …
New aryl-1, 3-thiazole-4-carbohydrazides, their 1, 3, 4-oxadiazole-2-thione, 1, 2, 4-triazole, isatin-3-ylidene and carboxamide derivatives. Synthesis and anti-HIV …
A series of isatin-3-ylidene (6a-i) and arylthiazolyl-1, 3, 4-oxadiazole-2-thione derivatives 7a-
i derived from arylthiazolyl carbohydrazide analogs 4a-i were synthesized. Analogously …
i derived from arylthiazolyl carbohydrazide analogs 4a-i were synthesized. Analogously …