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[HTML][HTML] Analytical techniques for the characterization and quantification of monoclonal antibodies
HA Alhazmi, M Albratty - Pharmaceuticals, 2023 - mdpi.com
Monoclonal antibodies (mAbs) are a fast-growing class of biopharmaceuticals. They are
widely used in the identification and detection of cell makers, serum analytes, and …
widely used in the identification and detection of cell makers, serum analytes, and …
Therapeutic Fc‐fusion proteins: current analytical strategies
BL Duivelshof, A Murisier, J Camperi… - Journal of separation …, 2021 - Wiley Online Library
Fc‐Fusion proteins represent a successful class of biopharmaceutical products, with already
13 drugs approved in the European Union and United States as well as three biosimilar …
13 drugs approved in the European Union and United States as well as three biosimilar …
Predicting antibody developability profiles through early stage discovery screening
M Bailly, C Mieczkowski, V Juan, E Metwally… - MAbs, 2020 - Taylor & Francis
Monoclonal antibodies play an increasingly important role for the development of new drugs
across multiple therapy areas. The term 'developability'encompasses the feasibility of …
across multiple therapy areas. The term 'developability'encompasses the feasibility of …
Blueprint for antibody biologics developability
C Mieczkowski, X Zhang, D Lee, K Nguyen, W Lv… - MAbs, 2023 - Taylor & Francis
Large-molecule antibody biologics have revolutionized medicine owing to their superior
target specificity, pharmacokinetic and pharmacodynamic properties, safety and toxicity …
target specificity, pharmacokinetic and pharmacodynamic properties, safety and toxicity …
Applications of capillary electromigration methods for separation and analysis of proteins (2017–mid 2021)–a review
S Štěpánová, V Kašička - Analytica Chimica Acta, 2022 - Elsevier
This paper provides a detailed overview of relevant developments in separation and
analysis of proteins by capillary electromigration (CE) methods in the period 2017–mid …
analysis of proteins by capillary electromigration (CE) methods in the period 2017–mid …
Strategies for capillary electrophoresis: Method development and validation for pharmaceutical and biological applications—Updated and completely revised edition
F Krebs, H Zagst, M Stein, R Ratih, R Minkner… - …, 2023 - Wiley Online Library
This review is in support of the development of selective, precise, fast, and validated
capillary electrophoresis (CE) methods. It follows up a similar article from 1998, Wätzig H …
capillary electrophoresis (CE) methods. It follows up a similar article from 1998, Wätzig H …
[HTML][HTML] Antibody conjugates-recent advances and future innovations
Monoclonal antibodies have evolved from research tools to powerful therapeutics in the past
30 years. Clinical success rates of antibodies have exceeded expectations, resulting in …
30 years. Clinical success rates of antibodies have exceeded expectations, resulting in …
Capillary electrophoresis‐mass spectrometry for intact protein analysis: Pharmaceutical and biomedical applications (2018–March 2023)
K Maráková, M Opetová… - Journal of Separation …, 2023 - Wiley Online Library
Capillary electrophoresis is recognized as a valued separation technique for its high
separation efficiency, low sample consumption, good economic and ecological aspects …
separation efficiency, low sample consumption, good economic and ecological aspects …
[HTML][HTML] Current green capillary electrophoresis and liquid chromatography methods for analysis of pharmaceutical and biomedical samples (2019–2023)–a review
Separation analytical methods, including liquid chromatography (LC) and capillary
electrophoresis (CE), in combination with an appropriate detection technique, are dominant …
electrophoresis (CE), in combination with an appropriate detection technique, are dominant …
Enhancement of recombinant adeno-associated virus activity by improved stoichiometry and homogeneity of capsid protein assembly
T Onishi, M Nonaka, T Maruno, Y Yamaguchi… - … Therapy Methods & …, 2023 - cell.com
Studies of recombinant adeno-associated virus (rAAV) revealed the mixture of full particles
with different densities in rAAV. There are no conclusive results because of the lack of …
with different densities in rAAV. There are no conclusive results because of the lack of …