Obesity cardiomyopathy: evidence, mechanisms, and therapeutic implications
The prevalence of heart failure is on the rise and imposes a major health threat, in part, due
to the rapidly increased prevalence of overweight and obesity. To this point …
to the rapidly increased prevalence of overweight and obesity. To this point …
Meta-analysis of penetrance and systematic review on transition to disease in genetic hypertrophic cardiomyopathy
BACKGROUND: Hypertrophic cardiomyopathy (HCM) is characterized by unexplained left
ventricular hypertrophy and is classically caused by pathogenic or likely pathogenic variants …
ventricular hypertrophy and is classically caused by pathogenic or likely pathogenic variants …
Obesity and COVID-19 pandemics: epidemiology, mechanisms, and management
Y Yang, Y Song, D Hou - Diabetes, Metabolic Syndrome and …, 2023 - Taylor & Francis
Obesity is a principle causative factor of various metabolic dysfunctions, chronic
inflammation, and multi-organ impairment. The global epidemic of obesity has constituted …
inflammation, and multi-organ impairment. The global epidemic of obesity has constituted …
[HTML][HTML] Western diet triggers cardiac dysfunction in heterozygous Mybpc3-targeted knock-in mice: a two-hit model of hypertrophic cardiomyopathy
Background and aim Phenotypic expression of hypertrophic cardiomyopathy (HCM) and
disease course are associated with unfavorable metabolic health. We investigated if …
disease course are associated with unfavorable metabolic health. We investigated if …
Comprehensive multicomponent cardiac rehabilitation in cardiac implantable electronic devices recipients: a consensus document from the European Association of …
Cardiac rehabilitation (CR) is a multidisciplinary intervention including patient assessment
and medical actions to promote stabilization, management of cardiovascular risk factors …
and medical actions to promote stabilization, management of cardiovascular risk factors …
Association between renin–angiotensin–aldosterone system blockade and clinical outcomes in patients with hypertension: real-world observation from a nationwide …
Objective We investigated the association between the use of ACEi, ARB, or non-renin–
angiotensin–aldosterone system inhibitors (non-RASi) and incident cardiovascular events in …
angiotensin–aldosterone system inhibitors (non-RASi) and incident cardiovascular events in …
Phenotypic Spectrum of Subclinical Sarcomere-Related Hypertrophic Cardiomyopathy and Transition to Overt Disease
Genetic hypertrophic cardiomyopathy (HCM) is classically caused by pathogenic/likely
pathogenic variants in sarcomere genes (G+). Currently, HCM is diagnosed if there is …
pathogenic variants in sarcomere genes (G+). Currently, HCM is diagnosed if there is …
Unraveling the genotype‐phenotype relationship in hypertrophic cardiomyopathy: obesity‐related cardiac defects as a major disease modifier
Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiomyopathy and is
characterized by asymmetric septal thickening and diastolic dysfunction. More than 1500 …
characterized by asymmetric septal thickening and diastolic dysfunction. More than 1500 …
Comparison of mortality and cause of death between adults with and without hypertrophic cardiomyopathy
Insufficient evidence is available comparing mortality and cause of death between general
hypertrophic cardiomyopathy (HCM) and general non-HCM populations. We aimed to …
hypertrophic cardiomyopathy (HCM) and general non-HCM populations. We aimed to …
[HTML][HTML] Association between cardiovascular risk factors and dilated and hypertrophic cardiomyopathy: Mendelian randomization analysis
C Zou, H Zou, Y Jiang, S Lai, J Liu - Nutrition, Metabolism and …, 2025 - Elsevier
Background and aims: Dilated cardiomyopathy is a major cause of heart failure, and
hypertrophic cardiomyopathy is a common cause of sudden cardiac death in young adults …
hypertrophic cardiomyopathy is a common cause of sudden cardiac death in young adults …