To PEGylate or not to PEGylate: Immunological properties of nanomedicine's most popular component, polyethylene glycol and its alternatives
Polyethylene glycol or PEG has a long history of use in medicine. Many conventional
formulations utilize PEG as either an active ingredient or an excipient. PEG found its use in …
formulations utilize PEG as either an active ingredient or an excipient. PEG found its use in …
The crown and the scepter: roles of the protein corona in nanomedicine
Engineering nanomaterials are increasingly considered promising and powerful biomedical
tools or devices for imaging, drug delivery, and cancer therapies, but few nanomaterials …
tools or devices for imaging, drug delivery, and cancer therapies, but few nanomaterials …
Poly (ethylene glycol) alternatives in biomedical applications
X Yao, C Qi, C Sun, F Huo, X Jiang - Nano Today, 2023 - Elsevier
Abstract Poly (ethylene glycol)(PEG) as gold standard has been extensively conjugated to
diagnostic and therapeutic agents or decorated on the surface of nanoplatforms, which is …
diagnostic and therapeutic agents or decorated on the surface of nanoplatforms, which is …
Poly (2-oxazoline) s based biomaterials: A comprehensive and critical update
Abstract Poly (2-oxazoline) s have been investigated for decades as biomaterials.
Pioneering early work suggested that hydrophilic poly (2-oxazoline) s are comparable to …
Pioneering early work suggested that hydrophilic poly (2-oxazoline) s are comparable to …
Surface functionalization of graphene‐based materials: Biological behavior, toxicology, and safe‐by‐design aspects
The increasing exploitation of graphene‐based materials (GBMs) is driven by their unique
properties and structures, which ignite the imagination of scientists and engineers. At the …
properties and structures, which ignite the imagination of scientists and engineers. At the …
Graphene oxide loaded with tumor-targeted peptide and anti-cancer drugs for cancer target therapy
R Li, Y Wang, J Du, X Wang, A Duan, R Gao, J Liu… - Scientific reports, 2021 - nature.com
In the present work, we constructed nanoscale graphene oxide (NGO) as a drug nanocarrier
to improve the process of tumor-targeted drug releases, promote cellular uptake and …
to improve the process of tumor-targeted drug releases, promote cellular uptake and …
Drug Delivery Systems Based on Poly (2‐oxazoline) s and Poly (2‐oxazine) s
O Sedlacek, R Hoogenboom - Advanced Therapeutics, 2020 - Wiley Online Library
Abstract Poly (2‐oxazoline) s (PAOx) represent an established class of polymer materials
with a wide range of applications. In contrast, the homologous poly (2‐oxazine) s (PAOzi) …
with a wide range of applications. In contrast, the homologous poly (2‐oxazine) s (PAOzi) …
Immunological Responses Induced by Blood Protein Coronas on Two-Dimensional MoS2 Nanosheets
D Baimanov, J Wu, R Chu, R Cai, B Wang, M Cao… - ACS …, 2020 - ACS Publications
Two-dimensional (2D) nanosheets (NSs) have a large surface area, high surface free
energy, and ultrathin structure, which enable them to more easily penetrate biological …
energy, and ultrathin structure, which enable them to more easily penetrate biological …
Bioinert, stealth or interactive: how surface chemistry of nanocarriers determines their fate in vivo
Nanocarriers (NCs) have emerged as powerful tools to improve drug solubility, to promote
drug transport across membranes, to protect their payload from premature degradation, and …
drug transport across membranes, to protect their payload from premature degradation, and …
Endocytosis and organelle targeting of nanomedicines in cancer therapy
X Wang, Y Qiu, M Wang, C Zhang, T Zhang… - International journal …, 2020 - Taylor & Francis
Nanomedicines (NMs) have played an increasing role in cancer therapy as carriers to
efficiently deliver therapeutics into tumor cells. For this application, the uptake of NMs by …
efficiently deliver therapeutics into tumor cells. For this application, the uptake of NMs by …