Biological properties of extracellular vesicles and their physiological functions

M Yáñez-Mó, PRM Siljander, Z Andreu… - Journal of …, 2015 - Taylor & Francis
In the past decade, extracellular vesicles (EVs) have been recognized as potent vehicles of
intercellular communication, both in prokaryotes and eukaryotes. This is due to their capacity …

Types and origins of bacterial membrane vesicles

M Toyofuku, N Nomura, L Eberl - Nature Reviews Microbiology, 2019 - nature.com
Most bacteria release membrane vesicles (MVs) that contain specific cargo molecules and
have diverse functions, including the transport of virulence factors, DNA transfer, interception …

Molecular basis of bacterial outer membrane permeability revisited

H Nikaido - Microbiology and molecular biology reviews, 2003 - Am Soc Microbiol
Gram-negative bacteria characteristically are surrounded by an additional membrane layer,
the outer membrane. Although outer membrane components often play important roles in …

Classification, functions, and clinical relevance of extracellular vesicles

E Van der Pol, AN Böing, P Harrison, A Sturk… - Pharmacological …, 2012 - Elsevier
Both eukaryotic and prokaryotic cells release small, phospholipid-enclosed vesicles into
their environment. Why do cells release vesicles? Initial studies showed that eukaryotic …

Biological functions and biogenesis of secreted bacterial outer membrane vesicles

A Kulp, MJ Kuehn - Annual review of microbiology, 2010 - annualreviews.org
Gram-negative bacteria produce outer membrane vesicles (OMVs) that contain biologically
active proteins and perform diverse biological processes. Unlike other secretion …

Biofilms: hot spots of horizontal gene transfer (HGT) in aquatic environments, with a focus on a new HGT mechanism

K Abe, N Nomura, S Suzuki - FEMS microbiology ecology, 2020 - academic.oup.com
Biofilms in water environments are thought to be hot spots for horizontal gene transfer (HGT)
of antibiotic resistance genes (ARGs). ARGs can be spread via HGT, though mechanisms …

Outer membrane vesicles (OMVs) of gram-negative bacteria: a perspective update

AT Jan - Frontiers in microbiology, 2017 - frontiersin.org
Outer Membrane Vesicles (OMVs) of Gram-negative bacteria are spherical membrane-
enclosed entities of endocytic origin. Reported in the consortia of different bacterial species …

Extracellular membrane vesicles in the three domains of life and beyond

S Gill, R Catchpole, P Forterre - FEMS microbiology reviews, 2019 - academic.oup.com
Cells from all three domains of life, Archaea, Bacteria and Eukarya, produce extracellular
vesicles (EVs) which are sometimes associated with filamentous structures known as …

Horizontal transfer of antibiotic resistance genes in the human gut microbiome

RS McInnes, GE McCallum, LE Lamberte… - Current opinion in …, 2020 - Elsevier
Highlights•The human gut microbiome harbours antibiotic resistance genes ('the
resistome').•Antibiotic resistance genes can spread in the gut microbiome through horizontal …

Bacterial outer membrane vesicles and the host–pathogen interaction

MJ Kuehn, NC Kesty - Genes & development, 2005 - genesdev.cshlp.org
Extracellular secretion of products is the major mechanism by which Gram-negative
pathogens communicate with and intoxicate host cells. Vesicles released from the envelope …