Toward the integration of machine learning and molecular modeling for designing drug delivery nanocarriers

XJ Gao, K Ciura, Y Ma, A Mikolajczyk… - Advanced …, 2024 - Wiley Online Library
The pioneering work on liposomes in the 1960s and subsequent research in controlled drug
release systems significantly advances the development of nanocarriers (NCs) for drug …

Transformation of metal-organic frameworks (MOFs) under different factors

Y **ang, S Wei, T Wang, H Li, Y Luo, B Shao… - Coordination Chemistry …, 2025 - Elsevier
Metal-organic frameworks (MOFs) have been widely used in physics, chemistry, and
medicine due to their large porosity and adjustable pores, high specific surface area, and …

Rational Design of Metal–Organic Frameworks for Pancreatic Cancer Therapy: from Machine Learning Screening to In Vivo Efficacy

F Melle, D Menon, J Conniot… - Advanced …, 2025 - Wiley Online Library
Despite improvements in cancer survival rates, metastatic and surgery‐resistant cancers,
such as pancreatic cancer, remain challenging, with poor prognoses and limited treatment …

Polyvalent DNA Patches Enable Metal–Organic Fameworks with Enhanced Structural Integrity, Biointerface Stability, and Cellular Uptake

Z Han, H Yu, B Liu - Chemistry of Materials, 2025 - ACS Publications
Metal–organic frameworks (MOFs) hold great promise as drug carriers and therapeutic
agents in biomedical applications. However, the limited stability of MOF-based carriers in …

Dual antibody-guided drug delivery systems using MOF-PQDs nanocomposites for precise tumor diagnosis and combination therapy

X Han, J Chen, Y Zhao, R Kang, Y Wei… - Chemical Engineering …, 2025 - Elsevier
Due to their versatile capability to modulate both structure and function, MOF-based
nanocomposites incorporating targeting ligands, bioimaging agents, and photosensitizers …

[PDF][PDF] Nanotechnology in Ankylosing Spondylitis: Advancements in Drug Delivery and Targeted Therapy

A Kumar, JS Chaudhary, A Dubey… - International Journal of …, 2024 - researchgate.net
Ankylosing spondylitis is a chronic inflammatory disorder primarily affecting the spine and
the sacroiliac joints, although it is now considered for new drug target possibilities. It is an …

Rapid synthesis of CuTA/Cur@ ZIF-8 multifunctional drug delivery system towards cancer treatment

LM Nguyen, GTQ Vu, QTH Ta, NH Nguyen… - Colloids and Surfaces A …, 2025 - Elsevier
The multifaceted progression of cancer requires the implementation of nano-drug delivery
systems (DDS) with enhanced functionalities to strengthen therapeutic effectiveness …

Thermo-and pH-responsive MOF-303 mediated P127 and Gelatin coating for combination drug release and liver cancer therapy

SS Dwitya, KS Lin, MT Weng, NV Mdlovu, LJ Lai… - Materials Today …, 2025 - Elsevier
Abstract Metal-organic frameworks (MOFs), particularly MOF-303, show promise for liver
cancer therapy due to their high surface areas and tunable pore sizes. This study compared …

Elucidation of the CO2 adsorption mechanism of [Zn2 (mtz) 2 (ox)] using neutron powder diffraction

L Bao, JH Li, RB Lin, J Wu, Z Tan, W **e, W Ji… - Chinese Chemical …, 2025 - Elsevier
Abstract Metal-organic framework [Zn 2 (tz) 2 (ox)](CALF-20) has attracted great attention
due to its excellent ability to capture carbon dioxide. There are great interests to develop …

[HTML][HTML] Hybrid Nanoplatforms Based on Photosensitizers and Metal/Covalent Organic Frameworks for Improved Cancer Synergistic Treatment Nano-Delivery …

A Magadla - Molecules, 2025 - mdpi.com
Researchers have extensively investigated photosensitizer (PS) derivatives for various
applications due to their superior photophysical and electrochemical properties. However …