Alcohol is one of the most widely consumed psychoactive drugs globally. Hazardous
drinking, defined by quantity and frequency of consumption, is associated with acute and …

Importance Alcohol consumption is associated with 88 000 US deaths annually. Although
routine screening for heavy alcohol use can identify patients with alcohol use disorder …

Importance Alcohol use disorder affects more than 28.3 million people in the United States
and is associated with increased rates of morbidity and mortality. Objective To compare …

Substance use disorders (SUDs) are highly prevalent and exact a large toll on individuals'
health, well‐being, and social functioning. Long‐lasting changes in brain networks involved …

Background Alcohol use disorder (AUD) is a chronic, relapsing brain disorder that accounts
for 5% of deaths annually, and there is an urgent need to develop new targets for …

Alcohol is a major contributor to global disease and a leading cause of preventable death,
causing approximately 88,000 deaths annually in the United States alone. Alcohol use …

Alcohol use disorder (AUD) is a highly prevalent but severely under-treated disorder, with
only three widely-approved pharmacotherapies. Given that AUD is a very heterogeneous …

The harmful use of alcohol has been estimated to cause approximately 3.3 million deaths
every year, corresponding to nearly 6% of all deaths globally. Therefore, the effective …

Rates of alcohol use disorder (AUD) have increased in women by 84% over the past ten
years relative to a 35% increase in men. This substantive increase in female drinking is …

Background Early liver transplantation for severe alcohol-related hepatitis is an emerging
treatment option. We aimed to assess the risk of alcohol relapse 2 years after early liver …