Sesquiterpenes and their derivatives-natural anticancer compounds: An update

T Abu-Izneid, A Rauf, MA Shariati, AA Khalil… - Pharmacological …, 2020 - Elsevier
Sesquiterpenes belong to the largest group of plant secondary metabolites, which consist of
three isoprene building units. These compounds are widely distributed in various …

Applications of sesquiterpene lactones: a review of some potential success cases

L Moujir, O Callies, PMC Sousa, F Sharopov… - Applied Sciences, 2020 - mdpi.com
Sesquiterpene lactones, a vast range of terpenoids isolated from Asteraceae species,
exhibit a broad spectrum of biological effects and several of them are already commercially …

Tomentosin reduces behavior deficits and neuroinflammatory response in MPTP-induced Parkinson's disease in mice

Y Fan, M Maghimaa, A Chinnathambi… - Journal of …, 2021 - dl.begellhouse.com
Parkinson's disease (PD) is the second most common neurodegenerative disease
worldwide. Tomentosin is an active compound isolated from the I. viscosa plant that has …

Thiazolidinone-linked1, 2, 3-triazoles with monoterpenic skeleton as new potential anticancer agents: Design, synthesis and molecular docking studies

A Oubella, AE El Mansouri, M Fawzi, A Bimoussa… - Bioorganic …, 2021 - Elsevier
Abstract A novel series of 1, 2, 3-triazole-thiazolidinone-carvone hybrid compounds has
been designed and synthesized using the copper-catalyzed Huisgen azide-alkyne 1, 3 …

Non-volatile natural products in plant glandular trichomes: chemistry, biological activities and biosynthesis

Y Liu, SX **g, SH Luo, SH Li - Natural product reports, 2019 - pubs.rsc.org
Covering: 1960s to end of August 2018 Plant glandular trichomes (GTs) are adaptive
structures that are well known as “phytochemical factories” due to their impressive capacity …

Pharmacological properties and mechanism insights of Moroccan anticancer medicinal plants: what are the next steps?

A Bouyahya, O Belmehdi, A Benjouad… - Industrial Crops and …, 2020 - Elsevier
Moroccan flora is rich in medicinal plants that are widely used in traditional medicine for the
treatment of various diseases including cancer. These plants have several bioactive …

Anticancer and anti-inflammatory effects of tomentosin: Cellular and molecular mechanisms

N El Omari, N El Menyiy, G Zengin, BH Goh, M Gallo… - Separations, 2021 - mdpi.com
Tomentosin is a natural compound known for its presence in some medicinal plants of the
Asteraceae family such as Inula viscosa. Recent studies have highlighted its anticancer and …

Research progress on antitumor mechanisms and molecular targets of Inula sesquiterpene lactones

F Cao, C Chu, JJ Qin, X Guan - Chinese Medicine, 2023 - Springer
The pharmacological effects of natural product therapy have received sigificant attention,
among which terpenoids such as sesquiterpene lactones stand out due to their biological …

Elucidation of rutin's role in inducing caspase-dependent apoptosis via HPV-E6 and E7 down-regulation in cervical cancer HeLa cells

P Pandey, F Khan, M Farhan, A Jafri - Bioscience Reports, 2021 - portlandpress.com
Over the recent few years rutin has gained wider attention in exhibiting inhibitory potential
against several oncotargets for inducing apoptotic and antiproliferative activity in several …

Tomentosin displays anti-carcinogenic effect in human osteosarcoma MG-63 cells via the induction of intracellular reactive oxygen species

CM Lee, J Lee, MJ Nam, YS Choi, SH Park - International journal of …, 2019 - mdpi.com
Tomentosin is a natural sesquiterpene lactone extracted from various plants and is widely
used as a medicine because it exhibits essential therapeutic properties. In this study, we …