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Neurobiological basis of stress resilience
EJ Nestler, SJ Russo - Neuron, 2024 - cell.com
A majority of humans faced with severe stress maintain normal physiological and behavioral
function, a process referred to as resilience. Such stress resilience has been modeled in …
function, a process referred to as resilience. Such stress resilience has been modeled in …
Precision medicine in complex diseases—Molecular subgrou** for improved prediction and treatment stratification
Complex diseases are caused by a combination of genetic, lifestyle, and environmental
factors and comprise common noncommunicable diseases, including allergies …
factors and comprise common noncommunicable diseases, including allergies …
Philosophy of psychiatry: theoretical advances and clinical implications
Work at the intersection of philosophy and psychiatry has an extensive and influential
history, and has received increased attention recently, with the emergence of professional …
history, and has received increased attention recently, with the emergence of professional …
Shared genetic architecture between irritable bowel syndrome and psychiatric disorders reveals molecular pathways of the gut-brain axis
Background Irritable bowel syndrome (IBS) often co-occurs with psychiatric and
gastrointestinal disorders. A recent genome-wide association study (GWAS) identified …
gastrointestinal disorders. A recent genome-wide association study (GWAS) identified …
Did the human genome project affect research on schizophrenia?
EF Torrey - Psychiatry Research, 2024 - Elsevier
Abstract The Human Genome Project was undertaken primarily to discover genetic causes
and better treatments for human diseases. Schizophrenia was targeted since three of the …
and better treatments for human diseases. Schizophrenia was targeted since three of the …
Post‐traumatic stress disorder: evolving conceptualization and evidence, and future research directions
The understanding of responses to traumatic events has been greatly influenced by the
introduction of the diagnosis of post‐traumatic stress disorder (PTSD). In this paper we …
introduction of the diagnosis of post‐traumatic stress disorder (PTSD). In this paper we …
The genetic landscape of basal ganglia and implications for common brain disorders
The basal ganglia are subcortical brain structures involved in motor control, cognition, and
emotion regulation. We conducted univariate and multivariate genome-wide association …
emotion regulation. We conducted univariate and multivariate genome-wide association …
[HTML][HTML] How real-world data can facilitate the development of precision medicine treatment in psychiatry
Precision medicine has the ambition to improve treatment response and clinical outcomes
through patient stratification and holds great potential for the treatment of mental disorders …
through patient stratification and holds great potential for the treatment of mental disorders …
Sexual trauma, Polygenic Scores, and Mental Health diagnoses and outcomes
Importance Leveraging real-world clinical biobanks to investigate the associations between
genetic and environmental risk factors for mental illness may help direct clinical screening …
genetic and environmental risk factors for mental illness may help direct clinical screening …
Mental health and lower urinary tract symptoms: results from the NHANES and Mendelian randomization study
X Zhang, L Ma, J Li, W Zhang, Y **e, Y Wang - Journal of psychosomatic …, 2024 - Elsevier
Background The clinical observations suggest a correlation between lower urinary tract
symptoms (LUTSs) and mental health problems. Nonetheless, establishing a direct causal …
symptoms (LUTSs) and mental health problems. Nonetheless, establishing a direct causal …