Tissue engineering and cell-based therapies for fractures and bone defects
Bone fractures and segmental bone defects are a significant source of patient morbidity and
place a staggering economic burden on the healthcare system. The annual cost of treating …
place a staggering economic burden on the healthcare system. The annual cost of treating …
[HTML][HTML] Calcium phosphates in biomedical applications: materials for the future?
Our populations are aging. Some experts predict that 30% of hospital beds will soon be
occupied by osteoporosis patients. Statistics show that 20% of patients suffering from an …
occupied by osteoporosis patients. Statistics show that 20% of patients suffering from an …
Imaging challenges in biomaterials and tissue engineering
Biomaterials are employed in the fields of tissue engineering and regenerative medicine
(TERM) in order to enhance the regeneration or replacement of tissue function and/or …
(TERM) in order to enhance the regeneration or replacement of tissue function and/or …
Stem cells associated with macroporous bioceramics for long bone repair: 6-to 7-year outcome of a pilot clinical study
Extensive bone loss is still a major problem in orthopedics. A number of different therapeutic
approaches have been developed and proposed, but so far none have proven to be fully …
approaches have been developed and proposed, but so far none have proven to be fully …
A tissue engineering approach to bone repair in large animal models and in clinical practice
R Cancedda, P Giannoni, M Mastrogiacomo - Biomaterials, 2007 - Elsevier
The repair of large segmental bone defects due to trauma, inflammation and tumor surgery
remains a major clinical problem. Animal models were developed to test bone repair by …
remains a major clinical problem. Animal models were developed to test bone repair by …
miR-149-3p regulates the switch between adipogenic and osteogenic differentiation of BMSCs by targeting FTO
Bone marrow-derived mesenchymal stem cells (BMSCs) have been suggested to possess
the capacity to differentiate into different cell lineages. Maintaining a balanced stem cell …
the capacity to differentiate into different cell lineages. Maintaining a balanced stem cell …
Mechanical and biological properties of ZnO, SiO2, and Ag2O doped plasma sprayed hydroxyapatite coating for orthopaedic and dental applications
In this study, we explored a ternary dopant system utilizing 0.25 wt% ZnO to induce
osteogenesis, 0.5 wt% SiO 2 to induce angiogenesis, and 2.0 wt% Ag 2 O to provide …
osteogenesis, 0.5 wt% SiO 2 to induce angiogenesis, and 2.0 wt% Ag 2 O to provide …
The therapeutic applications of multipotential mesenchymal/stromal stem cells in skeletal tissue repair
Four decades after the first isolation and characterization of clonogenic bone marrow
stromal cells or mesenchymal stem cells (MSC) in the laboratory of Dr. Alexander …
stromal cells or mesenchymal stem cells (MSC) in the laboratory of Dr. Alexander …
SiO2 and ZnO dopants in three-dimensionally printed tricalcium phosphate bone tissue engineering scaffolds enhance osteogenesis and angiogenesis in vivo
G Fielding, S Bose - Acta biomaterialia, 2013 - Elsevier
Calcium phosphate (CaP) scaffolds with three-dimensionally-interconnected pores play an
important role in mechanical interlocking and biological fixation in bone implant …
important role in mechanical interlocking and biological fixation in bone implant …
Stem cells from deciduous tooth repair mandibular defect in swine
Y Zheng, Y Liu, CM Zhang, HY Zhang… - Journal of dental …, 2009 - journals.sagepub.com
Stem cells from human exfoliated deciduous teeth have been identified as a new post-natal
stem cell population with multipotential differentiation capabilities, including regeneration of …
stem cell population with multipotential differentiation capabilities, including regeneration of …