The exploitation of host autophagy and ubiquitin machinery by Mycobacterium tuberculosis in sha** immune responses and host defense during infection
Intracellular pathogens have evolved various efficient molecular armaments to subvert
innate defenses. Cellular ubiquitination, a normal physiological process to maintain …
innate defenses. Cellular ubiquitination, a normal physiological process to maintain …
Mycobacterium tuberculosis-macrophage interaction: Molecular updates
H Bo, UAE Moure, Y Yang, J Pan, L Li… - Frontiers in cellular …, 2023 - frontiersin.org
Mycobacterium tuberculosis (Mtb), the causative agent of Tuberculosis (TB), remains a
pathogen of great interest on a global scale. This airborne pathogen affects the lungs, where …
pathogen of great interest on a global scale. This airborne pathogen affects the lungs, where …
Mycobacterium tuberculosis Protein PE6 (Rv0335c), a Novel TLR4 Agonist, Evokes an Inflammatory Response and Modulates the Cell Death Pathways in …
Mycobacterium tuberculosis (M. tb) is an intracellular pathogen that exploits moonlighting
functions of its proteins to interfere with host cell functions. PE/PPE proteins utilize host …
functions of its proteins to interfere with host cell functions. PE/PPE proteins utilize host …
Mycobacterium tuberculosis RipA Dampens TLR4-Mediated Host Protective Response Using a Multi-Pronged Approach Involving Autophagy, Apoptosis, Metabolic …
Reductive evolution has endowed Mycobacterium tuberculosis (M. tb) with moonlighting in
protein functions. We demonstrate that RipA (Rv1477), a peptidoglycan hydrolase, activates …
protein functions. We demonstrate that RipA (Rv1477), a peptidoglycan hydrolase, activates …
Antibodies as key mediators of protection against Mycobacterium tuberculosis
Q Wang, D Nag, SL Baldwin, RN Coler… - Frontiers in …, 2024 - frontiersin.org
Tuberculosis (TB) is caused by infection with the bacterial pathogen Mycobacterium
tuberculosis (M. tb) in the respiratory tract. There was an estimated 10.6 million people …
tuberculosis (M. tb) in the respiratory tract. There was an estimated 10.6 million people …
Mycobacterium tuberculosis specific protein Rv1509 evokes efficient innate and adaptive immune response indicative of protective Th1 immune signature
Dissecting the function (s) of proteins present exclusively in Mycobacterium tuberculosis (M.
tb) will provide important clues regarding the role of these proteins in mycobacterial …
tb) will provide important clues regarding the role of these proteins in mycobacterial …
Structural and Biophysical properties of therapeutically important proteins Rv1509 and Rv2231A of Mycobacterium tuberculosis
Through comparative analyses using BLASTp and BLASTn of the 25 target sequences, our
research identified two unique post-transcriptional modifiers, Rv1509 and Rv2231A, which …
research identified two unique post-transcriptional modifiers, Rv1509 and Rv2231A, which …
Chemical and Biological Characterization of Mycobacterium tuberculosis-Specific ESAT6-Like Proteins and Their Potentials in the Prevention of Tuberculosis and …
AS Mustafa - Medical Principles and Practice, 2023 - karger.com
Abstract Early Secreted Antigenic Target 6 kDa (ESAT6) is a potent immunogenic protein
secreted by the bacteria causing tuberculosis, ie, Mycobacterium tuberculosis. Another …
secreted by the bacteria causing tuberculosis, ie, Mycobacterium tuberculosis. Another …
An Immunoinformatics-Based Study of Mycobacterium tuberculosis Region of Difference-2 Uncharacterized Protein (Rv1987) as a Potential Subunit Vaccine Candidate for …
Mycobacterium tuberculosis (Mtb) is the pathogen that causes tuberculosis and develops
resistance to many of the existing drugs. The sole licensed TB vaccine, BCG, is unable to …
resistance to many of the existing drugs. The sole licensed TB vaccine, BCG, is unable to …
Mechanisms of immune evasion by Mycobacterium tuberculosis: the impact of T7SS and cell wall lipids on host defenses
Mycobacterium tuberculosis (M. tb) is one of the most successful human pathogens, causing
a severe and widespread infectious disease. The frequent emergence of multidrug-resistant …
a severe and widespread infectious disease. The frequent emergence of multidrug-resistant …