[HTML][HTML] Articular cartilage and osteochondral tissue engineering techniques: Recent advances and challenges

W Wei, H Dai - Bioactive materials, 2021 - Elsevier
In spite of the considerable achievements in the field of regenerative medicine in the past
several decades, osteochondral defect regeneration remains a challenging issue among …

3D bioprinting of cell‐laden hydrogels for improved biological functionality

SM Hull, LG Brunel, SC Heilshorn - Advanced Materials, 2022 - Wiley Online Library
The encapsulation of cells within gel‐phase materials to form bioinks offers distinct
advantages for next‐generation 3D bioprinting. 3D bioprinting has emerged as a promising …

Adipose, bone marrow and synovial joint-derived mesenchymal stem cells for cartilage repair

CR Fellows, C Matta, R Zakany, IM Khan… - Frontiers in …, 2016 - frontiersin.org
Current cell-based repair strategies have proven unsuccessful for treating cartilage defects
and osteoarthritic lesions, consequently advances in innovative therapeutics are required …

Essential steps in bioprinting: From pre-to post-bioprinting

P Datta, A Barui, Y Wu, V Ozbolat, KK Moncal… - Biotechnology …, 2018 - Elsevier
An increasing demand for directed assembly of biomaterials has inspired the development
of bioprinting, which facilitates the assembling of both cellular and acellular inks into well …

[HTML][HTML] Effects of dynamic mechanical stimulations on the regeneration of in vitro and in vivo cartilage tissue based on silk fibroin scaffold

M Gu, S Fan, G Zhou, K Ma, X Yao, Y Zhang - Composites Part B …, 2022 - Elsevier
Due to the lack of blood and nutrition supply, the repairing of cartilage defect has become a
challenging topic in clinical treatment. Herein, a unique porous scaffold based on …

A guide for using mechanical stimulation to enhance tissue-engineered articular cartilage properties

EY Salinas, JC Hu, K Athanasiou - Tissue Engineering Part B …, 2018 - liebertpub.com
The use of tissue-engineered articular cartilage (TEAC) constructs has the potential to
become a powerful treatment option for cartilage lesions resulting from trauma or early …

Influence of the mechanical environment on the regeneration of osteochondral defects

S Davis, M Roldo, G Blunn, G Tozzi… - … in Bioengineering and …, 2021 - frontiersin.org
Articular cartilage is a highly specialised connective tissue of diarthrodial joints which
provides a smooth, lubricated surface for joint articulation and plays a crucial role in the …

Cartilage tissue engineering using stem cells and bioprinting technology—barriers to clinical translation

SL Francis, C Di Bella, GG Wallace… - Frontiers in …, 2018 - frontiersin.org
There is no long-term treatment strategy for young and active patients with cartilage defects.
Early and effective joint preserving treatments in these patients are crucial in preventing the …

The challenge of cartilage integration: understanding a major barrier to chondral repair

A Trengove, C Di Bella, AJ O'Connor - Tissue Engineering Part B …, 2022 - liebertpub.com
Articular cartilage defects caused by injury frequently lead to osteoarthritis, a painful and
costly disease. Despite widely used surgical methods to treat articular cartilage defects and …

Bioreactors for tissue engineering: An update

J Zhao, M Griffin, J Cai, S Li, PEM Bulter… - Biochemical …, 2016 - Elsevier
One of the greatest puzzles in wound healing is how to substitute or replace the defect
caused by loss and damaged tissue or organs. In regenerative medicine, Tissue …