Cu-related agents for cancer therapies

C Wang, X Yang, C Dong, K Chai, J Ruan… - Coordination Chemistry …, 2023 - Elsevier
As an indispensable micronutrient, copper (Cu) plays an important role in promoting
metabolism and maintaining various basic biological functions. Copper homeostasis in the …

The versatile nature of indole containing Schiff bases: An Overview

T Sanjurani, P Barman - Polyhedron, 2024 - Elsevier
Carbonyl compounds such as aldehydes or ketones condense with amines to form Schiff
bases. The synthesis of Schiff bases containing indole rings yields a broad spectrum of …

Synthesis, spectroscopic characterizations, single crystal XRD, supramolecular assembly inspection via hirshfeld surface analysis, and DFT study of a hydroxy …

H Inac, M Ashfaq, N Dege, M Feizi-Dehnayebi… - Journal of Molecular …, 2024 - Elsevier
The current work describes the synthesis, characterization, and theoretical investigation of a
copper complex with a hydroxy functionalized Schiff base ligand. The complex [Cu (DHBEE) …

Rhodium (III)–Picolinamide Complexes Act as Anticancer and Antimetastasis Agents via Inducing Apoptosis and Autophagy

YQ Gu, K Yang, QY Yang, HQ Li, MQ Hu… - Journal of Medicinal …, 2023 - ACS Publications
As a continuation of our endeavors in discovering metal-based drugs with cytotoxic and
antimetastatic activities, herein, we reported the syntheses of 11 new rhodium (III) …

[HTML][HTML] Biological evaluation, DFT, MEP, HOMO-LUMO analysis and ensemble docking studies of Zn (II) complexes of bidentate and tetradentate Schiff base ligands …

Z Akbari, C Stagno, N Iraci, T Efferth, EA Omer… - Journal of Molecular …, 2024 - Elsevier
Two Schiff base ligands and some related bidentate and tetradentate Zn (II) complexes were
investigated for their biological activity profiles as anticancer agents by resazurin method …

Synthesis, characterization, crystal structure, DNA and HSA Interactions, and anticancer activity of a mononuclear Cu (II) complex with a Schiff base ligand containing …

SU Parsekar, K Paliwal, P Haldar, PKS Antharjanam… - ACS …, 2022 - ACS Publications
A mononuclear Cu (II) complex [Cu (HL)(o-phen)]· H2O (1)[H3L=, o-phen= 1, 10-
phenanthroline] was isolated from methanol, and its X-ray single-crystal structure was …

Novel zinc (II) and copper (II) complexes of 2-((2-hydroxyethyl) amino) quinoline-3-carbaldehyde for antibacterial and antioxidant activities: A combined experimental …

T Damena, MB Alem, D Zeleke, T Desalegn… - ACS …, 2022 - ACS Publications
In the present work, two novel complexes of zinc (II) and copper (II) were synthesized from
the ligand 2-((2-hydroxyethyl) amino) quinoline-3-carbaldehyde (H 2 L) in a 1: 2 metal-to …

Facile synthesis of novel NNO-tethered copper (ii) complexes: characterization details, theoretical studies, promising enzyme-like activities, and biomolecular …

S Mandal, R Naskar, AS Mondal, B Bera… - Dalton …, 2023 - pubs.rsc.org
Given the ubiquitous and multifaceted role of copper ions in various biological processes,
we report herein the one-pot facile synthesis, X-ray structure, Hirshfeld surface analysis …

Hydrazylpyridine salicylaldehyde–copper (ii)–1, 10-phenanthroline complexes as potential anticancer agents: synthesis, characterization and anticancer evaluation

Y Chen, Z Ke, L Yuan, M Liang, S Zhang - Dalton Transactions, 2023 - pubs.rsc.org
We synthesized and analyzed nine unique copper (II) hydrazylpyridine salicylaldehyde and
1, 10-phenanthroline complexes,[Cu (L1a)(phen)](Cugdupt1),[Cu (L2a)(phen)]·(CH3CN) …

Designing metal chelates of halogenated sulfonamide Schiff bases as potent nonplatinum anticancer drugs using spectroscopic, molecular docking and biological …

RMI Elsamra, MS Masoud, AM Ramadan - Scientific Reports, 2022 - nature.com
In this contribution, five Ni (II) complexes have been synthesized from sulfonamide-based
Schiff bases (SB1–SB5) that comprise bromo or iodo substituents in the salicylidene moiety …