Ferroptosis, a cell death process driven by iron-dependent phospholipid peroxidation, has
been implicated in various diseases. There are two major surveillance mechanisms to …

Estrogen receptor positive (ER+) breast cancer is the most common breast cancer
diagnosed annually in the US with endocrine-based therapy as standard-of-care for this …

Cancer therapy is on the brink of a significant transformation with the inclusion of patient-
derived organoids (PDOs) in drug development. These three-dimensional cell cultures …

Estrogen receptor positive (ER+) breast cancer (BCa) accounts for the highest proportion of
breast cancer-related deaths. While endocrine therapy is highly effective for this …

Breast cancer (BC) is a heterogenous disease, with prognosis and treatment options
depending on Estrogen, Progesterone receptor, and Human Epidermal Growth Factor …

Abstract Development of novel inhibitors is necessary to counteract the rising prevalence of
breast cancer (BC) in women in recent years, as evidenced by the side-effect profiles of a …

Background Cyclin-dependent kinase 4/6 inhibitors (CDK4/6i) represent the gold standard
of the hormone receptor positive human epidermal growth factor receptor 2 (HER-2) …

Breast cancer is the most commonly diagnosed cancer and a leading cause of cancer-
related death in females. The most prevalent breast cancer subtype, luminal A, is …

Breast cancer is a significant cause of cancer-related deaths for women in North Carolina,
particularly Black women. Research has shown that stress can contribute to the …

Breast cancer remains the most prevalent cancer in women globally, with increasing
incidences despite improved survival rates, emphasizing the need for enhanced diagnostics …