Antibiotic therapy has become increasingly ineffective against bacterial infections due to the
rise of resistance. In particular, ESKAPE pathogens (Enterococcus faecium, Staphylococcus …

Antimicrobial resistance (AMR) is a global crisis for human public health which threatens the
effective prevention and control of ever-increasing infectious diseases. The advent of …

Over the past few decades, we have witnessed a surge around the world in the emergence
of antibiotic-resistant bacteria. This global health threat arose mainly due to the overuse and …

The global threat to public health posed by emerging multidrug-resistant bacteria in the past
few years necessitates the development of novel approaches to combat bacterial infections …

Acinetobacter baumannii, a Gram-negative multidrug-resistant (MDR) bacterium, is now
recognized as one of the more common nosocomial pathogens. Because most clinical …

Biofilms are complex microbial microcolonies consisting of planktonic and dormant bacteria
bound to a surface. The bacterial cells within the biofilm are embedded within the …

The emergence of bacteria resistance to most of the currently available antibiotics has
become a critical therapeutic problem. The bacteria causing both hospital and community …

Antibiotics have the remarkable power to control bacterial infections. Unfortunately,
widespread use, whether regarded as prudent or not, has favored the emergence and …

Phages are recognized as the most abundant and diverse entities on the planet. Their
diversity is determined predominantly by their dynamic adaptation capacities when …

Endolysins and their derivatives have emerged in recent years as a novel class of
antibacterials, which have now entered the clinical phases. Their rapid mode-of-action and …