Lipolysis is the process by which triglycerides (TGs) are hydrolyzed to free fatty acids (FFAs)
and glycerol. In adipocytes, this is achieved by sequential action of adipose TG lipase …

In adipocytes the hydrolysis of TAG to produce fatty acids and glycerol under fasting
conditions or times of elevated energy demands is tightly regulated by neuroendocrine …

Numerous studies address the physiology of adipose tissue (AT). The interest surrounding
the physiology of AT is primarily the result of the epidemic outburst of obesity in various …

Adipose triglyceride lipase (ATGL) is the key-enzyme for the release of fatty acids (FAs) from
triacylglycerol (TG) stores during intracellular lipolysis producing FAs used for energy …

Obesity is reaching epidemic proportions and imposes major negative health crises and an
economic burden in both high and low income countries. The multifaceted nature of obesity …

Cell death-inducing DFF45-like effector (CIDE) family proteins including Cidea, Cideb and
Cidec/Fsp27 are expressed in many different tissues and are known as lipid droplet (LD) …

Excess or insufficient lipid storage in white adipose tissue lipid droplets is associated with
dyslipidemia, insulin resistance and increased risk for diabetes type 2. Thus, maintenance of …

In adipocytes, lipolysis is a highly regulated process involving hormonal signals, lipid droplet-
associated proteins, and lipases. The discovery of new lipid droplet-associated proteins …

Human adipocytes express high levels of two distinct lipid droplet proteins, fat specific
protein 27 (FSP27; also called CIDEC), a member of the CIDE family, and perilipin1 (PLIN1) …

The discovery of adipose triglyceride lipase (ATGL) and its coactivator comparative gene
identification-58 (CGI-58) provided a major paradigm shift in the understanding of …