The charming world of the extracellular matrix: a dynamic and protective network of the intestinal wall
The intestinal extracellular matrix (ECM) represents a complex network of proteins that not
only forms a support structure for resident cells but also interacts closely with them by …
only forms a support structure for resident cells but also interacts closely with them by …
The role of extracellular matrix components in inflammatory bowel diseases
A Derkacz, P Olczyk, K Olczyk… - Journal of Clinical …, 2021 - mdpi.com
The remodeling of extracellular matrix (ECM) within the intestine tissues, which
simultaneously involves an increased degradation of ECM components and excessive …
simultaneously involves an increased degradation of ECM components and excessive …
A specific calprotectin neo-epitope [CPa9-HNE] in serum from inflammatory bowel disease patients is associated with neutrophil activity and endoscopic severity
JH Mortensen, D Sinkeviciute… - Journal of Crohn's …, 2022 - academic.oup.com
Abstract Background and Aims Endoscopy and the use of faecal calprotectin [faecal CP] are
among the least-favoured methods for assessing disease activity by inflammatory bowel …
among the least-favoured methods for assessing disease activity by inflammatory bowel …
[HTML][HTML] The extracellular matrix in colorectal cancer and its metastatic settling–Alterations and biological implications
S Karlsson, H Nyström - Critical reviews in oncology/hematology, 2022 - Elsevier
Colorectal cancer (CRC) remains one of the most common cancers worldwide. Metastatic
disease is ultimately fatal when incurable. Cancer research has evolved to take the …
disease is ultimately fatal when incurable. Cancer research has evolved to take the …
Human intestinal myofibroblasts deposited collagen VI enhances adhesiveness for T cells–A novel mechanism for maintenance of intestinal inflammation
SN Lin, A Musso, J Wang, PK Mukherjee, GA West… - Matrix Biology, 2022 - Elsevier
Objective: Inflammatory bowel diseases (IBD) cause chronic intestinal damage and
extracellular matrix (ECM) remodeling. The ECM may play an active role in inflammation by …
extracellular matrix (ECM) remodeling. The ECM may play an active role in inflammation by …
Enzymatic cross-linking of collagens in organ fibrosis–resolution and assessment
M Pehrsson, JH Mortensen… - Expert Review of …, 2021 - Taylor & Francis
Introduction: Enzymatic cross-linking of the collagens within the extracellular matrix (ECM)
catalyzed by enzymes such as lysyl oxidase (LOX) and lysyl oxidase like-enzymes 1–4 …
catalyzed by enzymes such as lysyl oxidase (LOX) and lysyl oxidase like-enzymes 1–4 …
Inflammatory bowel disease-associated gut commensals degrade components of the extracellular matrix
AM Porras, H Zhou, Q Shi, X ** up tissue inflammation and fibrosis
Chronic inflammatory diseases cause profound alterations in tissue homeostasis, including
unchecked activation of immune and nonimmune cells leading to disease complications …
unchecked activation of immune and nonimmune cells leading to disease complications …
Recellularized colorectal cancer patient-derived scaffolds as in vitro pre-clinical 3D model for drug screening
Colorectal cancer (CRC) shows highly ineffective therapeutic management. An urgent
unmet need is the random assignment to adjuvant chemotherapy of high-risk stage II and …
unmet need is the random assignment to adjuvant chemotherapy of high-risk stage II and …