We present here a review of the photochemical and electrochemical applications of multi-
site proton-coupled electron transfer (MS-PCET) in organic synthesis. MS-PCETs are redox …

Thermal C–C bond cleavage reactions allow the construction of structurally diverse
molecular skeletons via predictable and efficient bond reorganizations. Visible light …

Late-stage functionalization (LSF) introduces functional group or structural modification at
the final stage of the synthesis of natural products, drugs, and complex compounds. It is …

Reactions that enable carbon–nitrogen, carbon–oxygen and carbon–carbon bond formation
lie at the heart of synthetic chemistry. However, substrate prefunctionalization is often …

The quest to find milder and more sustainable methods to generate highly reactive, carbon-
centred intermediates has led to a resurgence of interest in radical chemistry. In particular …

The past decade has witnessed the emergence of N-(acyloxy) phthalimides (NHPI esters)
and its derivatives at the forefront of synthetic methods facilitating the construction of diverse …

Organoborons have emerged as versatile building blocks in organic synthesis to achieve
molecular diversity and as carboxylic acid bioisosteres with broad applicability in drug …

A useful protocol for achieving decarboxylative cross-coupling (DCC) of redox-active esters
(RAE, isolated or generated in situ) and halo (hetero) arenes is reported. This pragmatically …

Herein we disclose a strategy to promote the hydrocarboxylation of unactivated alkenes
using photochemical activation of formate salts. We illustrate that an alternative initiation …

The conversion of widely available carboxylic acids into versatile boronic esters would be
highly enabling for synthesis. We found that this transformation can be effected by …