Highlights•IEC invasion is a crucial step in the life cycle of non-typhoidal Salmonella.•TTSS-
1 effectors SopE/E2 and particularly SipA mediate IEC invasion in mice.•Entry structures …

To infect and cause disease, bacterial pathogens must localize to specific regions of the host
where they possess the metabolic and defensive acumen for survival. Motile flagellated …

Pseudomonas aeruginosa, a leading cause of severe hospital-acquired pneumonia, causes
infections with up to 50% mortality rates in mechanically ventilated patients. Despite some …

Pseudomonas aeruginosa, a leading cause of severe hospital-acquired pneumonia, causes
infections with up to 50% mortality rates in mechanically ventilated patients. Despite some …

Virulence gene expression can represent a substantial fitness cost to pathogenic bacteria. In
the model entero-pathogen Salmonella Typhimurium (S. Tm), such cost favors emergence of …

Aim Coaggregation, a highly specific cell–cell interaction mechanism, plays a pivotal role in
multispecies biofilm formation. While it has been mostly studied in oral environments, its …

Both the bacterial flagellum and the evolutionary related injectisome encoded on the
Salmonella pathogenicity island 1 (SPI-1) play crucial roles during the infection cycle of …

Interactions between individual pathogenic microbes and host tissues involve fast and
dynamic processes that ultimately impact the outcome of infection. Using live-cell …

Background Salmonella enteritidis (SE) is a major zoonotic pathogen and causes infections
in a variety of hosts. The development of novel vaccines for SE is necessary to eradicate this …

Abstract The Gram-negative bacteria Salmonella enterica and Escherichia coli are important
model organisms, powerful prokaryotic expression platforms for biotechnological …