Scientific evidence is mounting that synthetic chemicals used as food additives may have
harmful impacts on health. Food additives are chemicals that are added to food to keep it …

The development of the vertebrate eyes is a complex process starting from anterior-posterior
and dorso-ventral patterning of the anterior neural tube, resulting in the formation of the eye …

The trabecular meshwork (TM) is located in the anterior segment of the eye and is
responsible for regulating the outflow of aqueous humor. Increased resistance to aqueous …

Congenital PAX6-aniridia, initially characterized by the absence of the iris, has progressively
been shown to be associated with other developmental ocular abnormalities and systemic …

The ocular lens is a model system for understanding important aspects of embryonic
development, such as cell specification and the spatiotemporally controlled formation of a …

During development of the anterior eye segment, cells that originate from the surface
epithelium or the neuroepithelium need to interact with mesenchymal cells, which …

Keratocytes of the corneal stroma secrete a specialized extracellular matrix essential for
vision. These quiescent cells exhibit limited capacity for self‐renewal and after cell division …

Ocular lens development represents an advantageous system in which to study regulatory
mechanisms governing cell fate decisions, extracellular signaling, cell and tissue …

Aniridia is a rare panocular disorder affecting the cornea, anterior chamber, iris, lens, retina,
macula and optic nerve. It occurs because of mutations in PAX6 on band p13 of …

Background Glaucoma is a group of optic neuropathies in which damage to the optic nerve
results in a distinctive pattern of irreversible vision loss. Elevations in the intraocular …