Origins of specificity in protein-DNA recognition
Specific interactions between proteins and DNA are fundamental to many biological
processes. In this review, we provide a revised view of protein-DNA interactions that …
processes. In this review, we provide a revised view of protein-DNA interactions that …
[HTML][HTML] A suite of tutorials for the WESTPA rare-events sampling software [Article v1. 0]
The weighted ensemble (WE) strategy has been demonstrated to be highly efficient in
generating pathways and rate constants for rare events such as protein folding and protein …
generating pathways and rate constants for rare events such as protein folding and protein …
[HTML][HTML] Making the bend: DNA tertiary structure and protein-DNA interactions
S Harteis, S Schneider - International journal of molecular sciences, 2014 - mdpi.com
DNA structure functions as an overlap** code to the DNA sequence. Rapid progress in
understanding the role of DNA structure in gene regulation, DNA damage recognition and …
understanding the role of DNA structure in gene regulation, DNA damage recognition and …
Parmbsc1: a refined force field for DNA simulations
We present parmbsc1, a force field for DNA atomistic simulation, which has been
parameterized from high-level quantum mechanical data and tested for nearly 100 systems …
parameterized from high-level quantum mechanical data and tested for nearly 100 systems …
Web 3DNA 2.0 for the analysis, visualization, and modeling of 3D nucleic acid structures
Abstract Web 3DNA (w3DNA) 2.0 is a significantly enhanced version of the widely used
w3DNA server for the analysis, visualization, and modeling of 3D nucleic-acid-containing …
w3DNA server for the analysis, visualization, and modeling of 3D nucleic-acid-containing …
Structure, folding and flexibility of co-transcriptional RNA origami
RNA origami is a method for designing RNA nanostructures that can self-assemble through
co-transcriptional folding with applications in nanomedicine and synthetic biology. However …
co-transcriptional folding with applications in nanomedicine and synthetic biology. However …
[HTML][HTML] Structural basis for Cas9 off-target activity
The target DNA specificity of the CRISPR-associated genome editor nuclease Cas9 is
determined by complementarity to a 20-nucleotide segment in its guide RNA. However …
determined by complementarity to a 20-nucleotide segment in its guide RNA. However …
AMOEBA polarizable atomic multipole force field for nucleic acids
The AMOEBA polarizable atomic multipole force field for nucleic acids is presented. Valence
and electrostatic parameters were determined from high-level quantum mechanical data …
and electrostatic parameters were determined from high-level quantum mechanical data …
Ethidium bromide interactions with DNA: an exploration of a classic DNA–ligand complex with unbiased molecular dynamics simulations
Visualization of double stranded DNA in gels with the binding of the fluorescent dye
ethidium bromide has been a basic experimental technique in any molecular biology …
ethidium bromide has been a basic experimental technique in any molecular biology …
[PDF][PDF] New functionality of RNAComposer: an application to shape the axis of miR160 precursor structure
RNAComposer is a fully automated, web-interfaced system for RNA 3D structure prediction,
freely available at http://rnacomposer. cs. put. poznan. pl/and http://rnacomposer. ibch …
freely available at http://rnacomposer. cs. put. poznan. pl/and http://rnacomposer. ibch …