Localization of the epileptogenic zone using high frequency oscillations
A Thomschewski, AS Hincapié, B Frauscher - Frontiers in neurology, 2019 - frontiersin.org
For patients with drug-resistant focal epilepsy, surgery is the therapy of choice in order to
achieve seizure freedom. Epilepsy surgery foremost requires the identification of the …
achieve seizure freedom. Epilepsy surgery foremost requires the identification of the …
Trends in the use of automated algorithms for the detection of high‐frequency oscillations associated with human epilepsy
High‐frequency oscillations (HFOs) in intracranial electroencephalography (EEG) are a
promising biomarker of the epileptogenic zone and tool for surgical planning. Many studies …
promising biomarker of the epileptogenic zone and tool for surgical planning. Many studies …
High‐frequency oscillations in the normal human brain
Objective High‐frequency oscillations (HFOs) are a promising biomarker for the
epileptogenic zone. It has not been possible, however, to differentiate physiological from …
epileptogenic zone. It has not been possible, however, to differentiate physiological from …
Developmental atlas of phase-amplitude coupling between physiologic high-frequency oscillations and slow waves
We investigated the developmental changes in high-frequency oscillation (HFO) and
Modulation Index (MI)–the coupling measure between HFO and slow-wave phase. We …
Modulation Index (MI)–the coupling measure between HFO and slow-wave phase. We …
Spatial distribution of interictal spikes fluctuates over time and localizes seizure onset
EC Conrad, SB Tomlinson, JN Wong, KF Oechsel… - Brain, 2020 - academic.oup.com
The location of interictal spikes is used to aid surgical planning in patients with medically
refractory epilepsy; however, their spatial and temporal dynamics are poorly understood. In …
refractory epilepsy; however, their spatial and temporal dynamics are poorly understood. In …
Characterizing physiological high-frequency oscillations using deep learning
Objective. Intracranially-recorded interictal high-frequency oscillations (HFOs) have been
proposed as a promising spatial biomarker of the epileptogenic zone. However, HFOs can …
proposed as a promising spatial biomarker of the epileptogenic zone. However, HFOs can …
Objective interictal electrophysiology biomarkers optimize prediction of epilepsy surgery outcome
Researchers have looked for rapidly-and objectively-measurable electrophysiology
biomarkers that accurately localize the epileptogenic zone. Promising candidates include …
biomarkers that accurately localize the epileptogenic zone. Promising candidates include …
High-frequency oscillations in epilepsy: what have we learned and what needs to be addressed
For the past 2 decades, high-frequency oscillations (HFOs) have been enthusiastically
studied by the epilepsy community. Emerging evidence shows that HFOs harbor great …
studied by the epilepsy community. Emerging evidence shows that HFOs harbor great …
Multi-feature localization of epileptic foci from interictal, intracranial EEG
Objective When considering all patients with focal drug-resistant epilepsy, as high as 40–
50% of patients suffer seizure recurrence after surgery. To achieve seizure freedom without …
50% of patients suffer seizure recurrence after surgery. To achieve seizure freedom without …
Graph theoretical measures of fast ripples support the epileptic network hypothesis
The epileptic network hypothesis and epileptogenic zone hypothesis are two theories of
ictogenesis. The network hypothesis posits that coordinated activity among interconnected …
ictogenesis. The network hypothesis posits that coordinated activity among interconnected …