Summary Period3 (Per3) is one of the most robustly rhythmic genes in humans and animals.
It plays a significant role in temporal organisation in peripheral tissues. The effects of PER3 …

Pancreatic cancer (PC) has a very high mortality rate globally. Despite ongoing efforts, its
prognosis has not improved significantly over the last two decades. Thus, further …

Self-sustained and synchronized to environmental stimuli, circadian clocks are under
genetic and epigenetic regulation. Recent findings have greatly increased our …

Investigating the methylation status of the circadian genes may contribute to a better
understanding of the shift work-related circadian disruption in individuals exposed to …

DNA methylation profiles within whole-blood samples have been reported to be associated
with colorectal cancer (CRC) occurrence and might enable risk stratification for CRC. We …

Background: Colorectal cancer (CRC) screening might be improved by using a measure of
prior risk to modulate screening intensity or the faecal immunochemical test threshold …

One of the supposed mechanisms that may lead to breast cancer (BC) is an alteration of
circadian gene expression and DNA methylation. We undertook an integrated approach to …

The relationship between gene-specific DNA methylation in peripheral blood leukocytes and
colorectal cancer (CRC) susceptibility is unclear. In this case-control study, the methylation …

Epigenetic changes of DNA, including methylation, have long been recognized as key
indicators of various diseases, including aging, cancer, and neurological disorders …

Background Colorectal cancer is one of the most common malignant tumors worldwide with
high morbidity and mortality. This study aimed to identify different methylation sites as new …