[HTML][HTML] Jet injectors: Perspectives for small volume delivery with lasers

J Schoppink, DF Rivas - Advanced drug delivery reviews, 2022 - Elsevier
Needle-free jet injectors have been proposed as an alternative to injections with hypodermic
needles. Currently, a handful of commercial needle-free jet injectors already exist. However …

Synergistic strategies of biomolecular transport technologies in transdermal healthcare systems

J Han, YJ Choi, SK Kang - Advanced Healthcare Materials, 2024 - Wiley Online Library
Transdermal healthcare systems have gained significant attention for their painless and
convenient drug administration, as well as their ability to detect biomarkers promptly …

Delivery strategies for skin: comparison of nanoliter jets, needles and topical solutions

K Cu, R Bansal, S Mitragotri… - Annals of biomedical …, 2020 - Springer
Drug diffusion within the skin with a needle-free micro-jet injection (NFI) device was
compared with two well-established delivery methods: topical application and solid needle …

Microfluidics control the ballistic energy of thermocavitation liquid jets for needle-free injections

L Oyarte Gálvez, A Fraters, HL Offerhaus… - Journal of Applied …, 2020 - pubs.aip.org
Illuminating a water solution with a focused continuous wave laser produces a strong local
heating of the liquid that leads to the nucleation of bubbles, also known as thermocavitation …

Needle-free jet injection of poly-(lactic acid) for atrophic acne scars: literature review and report of clinical cases

NK Rho, HJ Kim, HS Kim, W Lee - Journal of Clinical Medicine, 2024 - mdpi.com
Acne scars, particularly atrophic ones, present a persistent challenge in cosmetic medicine
and surgery, requiring extended and multifaceted treatment approaches. Poly-(lactic acid) …

Hydrodynamics of a dual-orifice needle-free jet injector

Y Rane, J Marston - Journal of Drug Delivery Science and Technology, 2024 - Elsevier
In the recent literature, it has been shown that an enhanced, multi-faceted, balanced
immune response can be generated using a combined intradermal (ID) and intramuscular …

Visualization of penetration of a high-speed focused microjet into gel and animal skin

A Kiyama, N Endo, S Kawamoto, C Katsuta… - Journal of …, 2019 - Springer
Realization of a needle-free drug delivery device can solve needle-caused problems.
Recently, attention has been given to the use of a focused liquid jet instead of the use of the …

Recent advances in mechanical force-assisted transdermal delivery of macromolecular drugs

R Wang, Q Bian, Y Xu, D Xu, J Gao - International journal of pharmaceutics, 2021 - Elsevier
The transdermal delivery of macromolecular drugs has become one of the focused topics in
pharmaceutical research since it enables highly specific and effective delivery, while …

Characterization of jets for impulsively-started needle-free jet injectors: Influence of fluid properties

P Rohilla, YS Rane, I Lawal, A Le Blanc, J Davis… - Journal of Drug Delivery …, 2019 - Elsevier
An experimental study was performed to assess the hydrodynamics of liquid jets used for
needle-free injection, where the typical orifice diameter is~ 155 μm and velocity is in range …

Effect of geometrical parameters on the fluid dynamics of air-powered needle-free jet injectors

A Mohizin, JK Kim - Computers in Biology and Medicine, 2020 - Elsevier
Needle-free jet injectors are non-invasive systems having intradermal drug delivery
capabilities. At present, they revolutionize the next phase of drug delivery and therapeutic …