Bioactive sucralfate-based microneedles promote wound healing through reprogramming macrophages and protecting endogenous growth factors

Z Le, MC Ramos, Y Shou, RR Li, HS Cheng, CJM Jang… - Biomaterials, 2024 - Elsevier
Impaired wound healing due to insufficient cell proliferation and angiogenesis is a
significant physical and psychological burden to patients worldwide. Therapeutic delivery of …

Microenvironment-responsive nanomedicines: a promising direction for tissue regeneration

Y **ong, BB Mi, MA Shahbazi, T **a, J **ao - Military Medical Research, 2024 - Springer
Severe tissue defects present formidable challenges to human health, persisting as major
contributors to mortality rates. The complex pathological microenvironment, particularly the …

Engineered Enucleated Mesenchymal Stem Cells Regulating Immune Microenvironment and Promoting Wound Healing

Z Chen, Y Zou, H Sun, Y He, K Ye, Y Li… - Advanced …, 2024 - Wiley Online Library
Persistent excessive inflammation caused by neutrophil and macrophage dysfunction in the
wound bed leads to refractory response during wound healing. However, previous studies …

[HTML][HTML] Dysbiosis and diabetic foot ulcers: A metabolic perspective of Staphylococcus aureus infection

R Liu, J Feng, Y Ni, K Chen, Y Wang, T Zhang… - Biomedicine & …, 2024 - Elsevier
Staphylococcus aureus (S. aureus) infection is the most prevalent and resistant bacterial
infection, posing a worldwide health risk. Compared with healthy people, diabetes patients …

Multimodal integrated flexible neural probe for in situ monitoring of EEG and lactic acid

L Zhang, J **a, B Li, Z Cao, S Dong - RSC advances, 2024 - pubs.rsc.org
In physiological activities, the brain's electroencephalogram (EEG) signal and chemical
concentration change are crucial for diagnosing and treating neurological disorders. Despite …

[HTML][HTML] Macrophages: Key players in diabetic wound healing

X Zhou, YL Guo, C Xu, J Wang - World Journal of Diabetes, 2024 - pmc.ncbi.nlm.nih.gov
In this editorial, we discuss the article by Wen et al published. Diabetic foot ulcers are
prevalent and serious complications of diabetes, significantly impacting patients' quality of …

Cortical Response to Acute Implantation of the Utah Optrode Array in Macaque Cortex

A Villamarin-Ortiz, CF Reiche, F Federer, AM Clark… - bioRxiv, 2025 - biorxiv.org
Optogenetics has transformed the study of neural circuit function, but limitations in its
application to species with large brains, such as non-human primates (NHPs), remain. A …

Using ionizable guanidine to develop cholesterol-free three-component lipid nanoparticles for spleen-targeted mRNA delivery

M Li, H Zhang, D Liu, Z Liang - 2024 - researchsquare.com
Lipid nanoparticle (LNP) represents a key breakthrough in the realm of RNA therapeutics,
particularly for the development of mRNA therapeutics and vaccines. Most LNPs developed …