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Nanomedicine tumor targeting
T Lammers - Advanced Materials, 2024 - Wiley Online Library
Nanomedicines are extensively explored for cancer therapy. By delivering drug molecules
more efficiently to pathological sites and by attenuating their accumulation in healthy organs …
more efficiently to pathological sites and by attenuating their accumulation in healthy organs …
Designing drug delivery systems for cell therapy
Cell therapies, such as immune cell and stem cell therapies, are being preclinically and
clinically explored for the treatment of various diseases, but are often limited by low efficacy …
clinically explored for the treatment of various diseases, but are often limited by low efficacy …
Neutrophils bearing adhesive polymer micropatches as a drug-free cancer immunotherapy
Tumour-associated neutrophils can exert antitumour effects but can also assume a pro-
tumoural phenotype in the immunosuppressive tumour microenvironment. Here we show …
tumoural phenotype in the immunosuppressive tumour microenvironment. Here we show …
Polymer micropatches as natural killer cell engagers for tumor therapy
Natural killer (NK) cell therapies have emerged as a potential therapeutic approach to
various cancers. Their efficacy, however, is limited by their low persistence and anergy …
various cancers. Their efficacy, however, is limited by their low persistence and anergy …
[HTML][HTML] ROS-responsive nanoparticle delivery of ferroptosis inhibitor prodrug to facilitate mesenchymal stem cell-mediated spinal cord injury repair
R Hua, C Zhao, Z Xu, D Liu, W Shen, W Yuan, Y Li… - Bioactive Materials, 2024 - Elsevier
Spinal cord injury (SCI) is a traumatic condition that results in impaired motor and sensory
function. Ferroptosis is one of the main causes of neural cell death and loss of neurological …
function. Ferroptosis is one of the main causes of neural cell death and loss of neurological …
Cell-mediated nanoparticle delivery systems: towards precision nanomedicine
Cell-mediated nanoparticle delivery systems (CMNDDs) utilize cells as carriers to deliver the
drug-loaded nanoparticles. Unlike the traditional nanoparticle drug delivery approaches …
drug-loaded nanoparticles. Unlike the traditional nanoparticle drug delivery approaches …
Emerging strategies for nanomedicine in autoimmunity
Autoimmune disorders have risen to be among the most prevalent chronic diseases across
the globe, affecting approximately 5–7% of the population. As autoimmune diseases steadily …
the globe, affecting approximately 5–7% of the population. As autoimmune diseases steadily …
Polymer backpack‐loaded tissue infiltrating monocytes for treating cancer
Adoptive cell therapies are dramatically altering the treatment landscape of cancer.
However, treatment of solid tumors remains a major unmet need, in part due to limited …
However, treatment of solid tumors remains a major unmet need, in part due to limited …
[HTML][HTML] Current knowledge about nonclassical monocytes in patients with multiple sclerosis, a systematic review
B Arneth - International Journal of Molecular Sciences, 2024 - mdpi.com
Monocytes play a critical role in the initiation and progression of multiple sclerosis (MS).
Recent research indicates the importance of considering the roles of monocytes in the …
Recent research indicates the importance of considering the roles of monocytes in the …
The plasticity of immune cell response complicates dissecting the underlying pathology of multiple sclerosis
SK Sarkar, AML Willson… - Journal of Immunology …, 2024 - Wiley Online Library
Multiple sclerosis (MS) is a neurodegenerative autoimmune disease characterized by the
destruction of the myelin sheath of the neuronal axon in the central nervous system. Many …
destruction of the myelin sheath of the neuronal axon in the central nervous system. Many …