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A review on computational systems biology of pathogen–host interactions
Pathogens manipulate the cellular mechanisms of host organisms via pathogen–host
interactions (PHIs) in order to take advantage of the capabilities of host cells, leading to …
interactions (PHIs) in order to take advantage of the capabilities of host cells, leading to …
(Differential) co-expression analysis of gene expression: a survey of best practices
Analysis of gene expression data is widely used in transcriptomic studies to understand
functions of molecules inside a cell and interactions among molecules. Differential co …
functions of molecules inside a cell and interactions among molecules. Differential co …
[HTML][HTML] Two's company: studying interspecies relationships with dual RNA-seq
Organisms do not exist isolated from each other, but constantly interact. Cells can sense the
presence of interaction partners by a range of receptors and, via complex regulatory …
presence of interaction partners by a range of receptors and, via complex regulatory …
Differential expression analysis of RNA-seq reads: overview, taxonomy, and tools
Analysis of RNA-sequence (RNA-seq) data is widely used in transcriptomic studies and it
has many applications. We review RNA-seq data analysis from RNA-seq reads to the results …
has many applications. We review RNA-seq data analysis from RNA-seq reads to the results …
Cancer microarray data feature selection using multi-objective binary particle swarm optimization algorithm
Cancer investigations in microarray data play a major role in cancer analysis and the
treatment. Cancer microarray data consists of complex gene expressed patterns of cancer …
treatment. Cancer microarray data consists of complex gene expressed patterns of cancer …
[HTML][HTML] DiffBrainNet: Differential analyses add new insights into the response to glucocorticoids at the level of genes, networks and brain regions
Genome-wide gene expression analyses are invaluable tools for studying biological and
disease processes, allowing a hypothesis-free comparison of expression profiles …
disease processes, allowing a hypothesis-free comparison of expression profiles …
Candida albicans infection leads to barrier breakdown and a MAPK/NF‐κB mediated stress response in the intestinal epithelial cell line C2BBe1
M Böhringer, S Pohlers, S Schulze… - Cellular …, 2016 - Wiley Online Library
Intestinal epithelial cells (IEC) form a tight barrier to the gut lumen. Paracellular permeability
of the intestinal barrier is regulated by tight junction proteins and can be modulated by …
of the intestinal barrier is regulated by tight junction proteins and can be modulated by …
A strategy to incorporate prior knowledge into correlation network cutoff selection
Correlation networks are frequently used to statistically extract biological interactions
between omics markers. Network edge selection is typically based on the statistical …
between omics markers. Network edge selection is typically based on the statistical …
Network medicine: From conceptual frameworks to applications and future trends
The intricate nature of biological processes is orchestrated by molecular interactions. The
complexity of these interactions stems from the sheer number of components involved and …
complexity of these interactions stems from the sheer number of components involved and …
Results and lessons learned from the sbv IMPROVER metagenomics diagnostics for inflammatory bowel disease challenge
A growing body of evidence links gut microbiota changes with inflammatory bowel disease
(IBD), raising the potential benefit of exploiting metagenomics data for non-invasive IBD …
(IBD), raising the potential benefit of exploiting metagenomics data for non-invasive IBD …