A review on computational systems biology of pathogen–host interactions

S Durmuş, T Çakır, A Özgür, R Guthke - Frontiers in microbiology, 2015 - frontiersin.org
Pathogens manipulate the cellular mechanisms of host organisms via pathogen–host
interactions (PHIs) in order to take advantage of the capabilities of host cells, leading to …

(Differential) co-expression analysis of gene expression: a survey of best practices

HA Chowdhury, DK Bhattacharyya… - IEEE/ACM transactions …, 2019 - ieeexplore.ieee.org
Analysis of gene expression data is widely used in transcriptomic studies to understand
functions of molecules inside a cell and interactions among molecules. Differential co …

[HTML][HTML] Two's company: studying interspecies relationships with dual RNA-seq

T Wolf, P Kämmer, S Brunke, J Linde - Current opinion in microbiology, 2018 - Elsevier
Organisms do not exist isolated from each other, but constantly interact. Cells can sense the
presence of interaction partners by a range of receptors and, via complex regulatory …

Differential expression analysis of RNA-seq reads: overview, taxonomy, and tools

HA Chowdhury, DK Bhattacharyya… - IEEE/ACM transactions …, 2018 - ieeexplore.ieee.org
Analysis of RNA-sequence (RNA-seq) data is widely used in transcriptomic studies and it
has many applications. We review RNA-seq data analysis from RNA-seq reads to the results …

Cancer microarray data feature selection using multi-objective binary particle swarm optimization algorithm

CSR Annavarapu, S Dara, H Banka - EXCLI journal, 2016 - pmc.ncbi.nlm.nih.gov
Cancer investigations in microarray data play a major role in cancer analysis and the
treatment. Cancer microarray data consists of complex gene expressed patterns of cancer …

[HTML][HTML] DiffBrainNet: Differential analyses add new insights into the response to glucocorticoids at the level of genes, networks and brain regions

N Gerstner, AC Krontira, C Cruceanu, S Roeh… - Neurobiology of …, 2022 - Elsevier
Genome-wide gene expression analyses are invaluable tools for studying biological and
disease processes, allowing a hypothesis-free comparison of expression profiles …

Candida albicans infection leads to barrier breakdown and a MAPK/NF‐κB mediated stress response in the intestinal epithelial cell line C2BBe1

M Böhringer, S Pohlers, S Schulze… - Cellular …, 2016 - Wiley Online Library
Intestinal epithelial cells (IEC) form a tight barrier to the gut lumen. Paracellular permeability
of the intestinal barrier is regulated by tight junction proteins and can be modulated by …

A strategy to incorporate prior knowledge into correlation network cutoff selection

E Benedetti, M Pučić-Baković, T Keser… - Nature …, 2020 - nature.com
Correlation networks are frequently used to statistically extract biological interactions
between omics markers. Network edge selection is typically based on the statistical …

Network medicine: From conceptual frameworks to applications and future trends

ES Ayar, S Dadmand, N Tuncbag - IEEE Transactions on …, 2023 - ieeexplore.ieee.org
The intricate nature of biological processes is orchestrated by molecular interactions. The
complexity of these interactions stems from the sheer number of components involved and …

Results and lessons learned from the sbv IMPROVER metagenomics diagnostics for inflammatory bowel disease challenge

L Khachatryan, Y **ang, A Ivanov, E Glaab… - Scientific Reports, 2023 - nature.com
A growing body of evidence links gut microbiota changes with inflammatory bowel disease
(IBD), raising the potential benefit of exploiting metagenomics data for non-invasive IBD …