IMI–Report on experimental models of emmetropization and myopia

D Troilo, EL Smith, DL Nickla, R Ashby… - … & visual science, 2019 - iovs.arvojournals.org
The results of many studies in a variety of species have significantly advanced our
understanding of the role of visual experience and the mechanisms of postnatal eye growth …

Light as a central modulator of circadian rhythms, sleep and affect

TA LeGates, DC Fernandez, S Hattar - Nature Reviews Neuroscience, 2014 - nature.com
Light has profoundly influenced the evolution of life on earth. As widely appreciated, light
enables us to generate images of our environment. However, light—through intrinsically …

Retinal ganglion cells—diversity of cell types and clinical relevance

US Kim, OA Mahroo, JD Mollon… - Frontiers in neurology, 2021 - frontiersin.org
Retinal ganglion cells (RGCs) are the bridging neurons that connect the retinal input to the
visual processing centres within the central nervous system. There is a remarkable diversity …

Diversity of intrinsically photosensitive retinal ganglion cells: circuits and functions

ML Aranda, TM Schmidt - Cellular and Molecular Life Sciences, 2021 - Springer
The melanopsin-expressing, intrinsically photosensitive retinal ganglion cells (ipRGCs) are
a relatively recently discovered class of atypical ganglion cell photoreceptor. These ipRGCs …

Melanopsin and the intrinsically photosensitive retinal ganglion cells: biophysics to behavior

MTH Do - Neuron, 2019 - cell.com
The mammalian visual system encodes information over a remarkable breadth of
spatiotemporal scales and light intensities. This performance originates with its complement …

The RNA binding protein RBPMS is a selective marker of ganglion cells in the mammalian retina

AR Rodriguez, LP de Sevilla Müller… - Journal of …, 2014 - Wiley Online Library
There are few neurochemical markers that reliably identify retinal ganglion cells (RGCs),
which are a heterogeneous population of cells that integrate and transmit the visual signal …

Circadian photoentrainment in mice and humans

RG Foster, S Hughes, SN Peirson - Biology, 2020 - mdpi.com
Light around twilight provides the primary entrainment signal for circadian rhythms. Here we
review the mechanisms and responses of the mouse and human circadian systems to light …

Intrinsically photosensitive retinal ganglion cells: many subtypes, diverse functions

TM Schmidt, SK Chen, S Hattar - Trends in neurosciences, 2011 - cell.com
For decades, rods and cones were thought to be the only photoreceptors in the mammalian
retina. However, a population of atypical photoreceptive retinal ganglion cells (RGCs) …

Melanopsin-expressing retinal ganglion-cell photoreceptors: cellular diversity and role in pattern vision

JL Ecker, ON Dumitrescu, KY Wong, NM Alam… - Neuron, 2010 - cell.com
Using the photopigment melanopsin, intrinsically photosensitive retinal ganglion cells
(ipRGCs) respond directly to light to drive circadian clock resetting and pupillary constriction …

Effects of smartphone use with and without blue light at night in healthy adults: A randomized, double-blind, cross-over, placebo-controlled comparison

JY Heo, K Kim, M Fava, D Mischoulon… - Journal of psychiatric …, 2017 - Elsevier
Smartphones deliver light to users through Light Emitting Diode (LED) displays. Blue light is
the most potent wavelength for sleep and mood. This study investigated the immediate …