Image analysis of the mitochondrial network morphology with applications in cancer research
Mitochondria are dynamic organelles that integrate bioenergetics, biosynthesis, and
signaling in cells and regulate redox homeostasis, apoptotic pathways, and cell proliferation …
signaling in cells and regulate redox homeostasis, apoptotic pathways, and cell proliferation …
Mitochondrial dynamics in drug-induced liver injury
Mitochondria have been studied for decades from the standpoint of metabolism and ATP
generation. However, in recent years mitochondrial dynamics and its influence on …
generation. However, in recent years mitochondrial dynamics and its influence on …
A sensitive NIR mitochondria-targeting fluorescence probe for visualizing viscosity in living cells and mice
Mitochondria are the powerhouses in cells, providing the energy needed for cellular
activities. However, the abnormalities in the mitochondrial microenvironment (eg, the …
activities. However, the abnormalities in the mitochondrial microenvironment (eg, the …
Diesel exhaust particles alter mitochondrial bioenergetics and cAMP producing capacity in human bronchial epithelial cells
Introduction: Air pollution from diesel combustion is linked in part to the generation of diesel
exhaust particles (DEP). DEP exposure induces various processes, including inflammation …
exhaust particles (DEP). DEP exposure induces various processes, including inflammation …
Teriflunomide/leflunomide synergize with chemotherapeutics by decreasing mitochondrial fragmentation via DRP1 in SCLC
T Mirzapoiazova, L Tseng, B Mambetsariev, H Li… - iScience, 2024 - cell.com
Although up to 80% small-cell lung cancer (SCLC) patients response good for first-line
chemotherapy regimen, most patients develop recurrence of the disease within weeks to …
chemotherapy regimen, most patients develop recurrence of the disease within weeks to …
Infection of endothelial cells with Acinetobacter baumannii reveals remodelling of mitochondrial protein complexes
L Leukert, M Tietgen, FF Krause… - Microbiology …, 2023 - Am Soc Microbiol
Acinetobacter baumannii is an antibiotic-resistant, Gram-negative pathogen that causes a
multitude of nosocomial infections. However, pathogenicity mechanisms and the host cell …
multitude of nosocomial infections. However, pathogenicity mechanisms and the host cell …
Simulation-supervised deep learning for analysing organelles states and behaviour in living cells
In many real-world scientific problems, generating ground truth (GT) for supervised learning
is almost impossible. The causes include limitations imposed by scientific instrument …
is almost impossible. The causes include limitations imposed by scientific instrument …
Physics of cellular energy metabolism
Contributions to the field of cellular energy metabolism have been dominated by
biochemistry. Over the past decade, however, several physics-based approaches have …
biochemistry. Over the past decade, however, several physics-based approaches have …
Presenting CODS (Cell Organelle Dynamic Simulation)
A Celeste - 2023 - munin.uit.no
The interactions between organelles within living cells have an effect on the health of the
organism [1]. One way to study this behavior is to develop algorithms which can …
organism [1]. One way to study this behavior is to develop algorithms which can …