New clinical trial design in precision medicine: discovery, development and direction
XP Duan, BD Qin, XD Jiao, K Liu, Z Wang… - Signal Transduction and …, 2024 - nature.com
In the era of precision medicine, it has been increasingly recognized that individuals with a
certain disease are complex and different from each other. Due to the underestimation of the …
certain disease are complex and different from each other. Due to the underestimation of the …
Potential of CDC25 phosphatases in cancer research and treatment: key to precision medicine
The global burden of cancer continues to rise, underscoring the urgency of develo** more
effective and precisely targeted therapies. This comprehensive review explores the …
effective and precisely targeted therapies. This comprehensive review explores the …
Digital twins as global learning health and disease models for preventive and personalized medicine
Ineffective medication is a major healthcare problem causing significant patient suffering
and economic costs. This issue stems from the complex nature of diseases, which involve …
and economic costs. This issue stems from the complex nature of diseases, which involve …
Role of liposomes in chemoimmunotherapy of Breast cancer
In the dynamic arena of cancer therapeutics, chemoimmunotherapy has shown tremendous
promise, especially for aggressive forms of breast cancer like triple-negative breast cancer …
promise, especially for aggressive forms of breast cancer like triple-negative breast cancer …
Advancing precision medicine: the transformative role of artificial intelligence in immunogenomics, radiomics, and pathomics for biomarker discovery and …
L Chang, J Liu, J Zhu, S Guo, Y Wang… - Cancer Biology & …, 2025 - cancerbiomed.org
Artificial intelligence (AI) is significantly advancing precision medicine, particularly in the
fields of immunogenomics, radiomics, and pathomics. In immunogenomics, AI can process …
fields of immunogenomics, radiomics, and pathomics. In immunogenomics, AI can process …
[HTML][HTML] Synergistic Effects of Mistletoe Lectin and Cisplatin on Triple-Negative Breast Cancer Cells: Insights from 2D and 3D In Vitro Models
SY Lyu, SM Meshesha, CE Hong - International Journal of Molecular …, 2025 - mdpi.com
Triple-negative breast cancer (TNBC) remains a challenging subtype due to its aggressive
nature and limited treatment options. This study investigated the potential synergistic effects …
nature and limited treatment options. This study investigated the potential synergistic effects …
Analysis of the Effects of Bevacizumab Combined with Chemoradiotherapy on VEGF, bFGF, and Let-7 Levels in Non-Small Cell Lung Cancer and the Factors …
XC Luo, P Tang, PX Zhong - International Journal of General …, 2024 - Taylor & Francis
Objective To explore the influence of bevacizumab combined with chemoradiotherapy on
VEGF, bFGF, and Let-7 in patients with non-small cell lung cancer (NSCLC), and to analyze …
VEGF, bFGF, and Let-7 in patients with non-small cell lung cancer (NSCLC), and to analyze …
Drug Repositioning Using Single-Cell RNA Sequencing in Cancer Research
Single-cell RNA sequencing (scRNA-seq) is a valuable tool for investigating cellular
dynamics at the transcriptome level, enabling researchers to delve into the interactions of …
dynamics at the transcriptome level, enabling researchers to delve into the interactions of …
The Interplay between p53 and the Tumor Microenvironment in Progressing Breast Cancer
Breast cancer represents a multifaceted oncological challenge characterized by
dysregulated cellular proliferation within mammary tissue and is a significant global health …
dysregulated cellular proliferation within mammary tissue and is a significant global health …
[PDF][PDF] Digital Twins as Global Learning Health and Disease Models of Individuals
Emerging molecular and computational techniques may allow construction and
computational treatment of dynamic digital twins on the scale of populations to individuals …
computational treatment of dynamic digital twins on the scale of populations to individuals …