AI in the clinical management of GA: a novel therapeutic universe requires novel tools
GS Reiter, J Mai, S Riedl, K Birner, S Frank… - Progress in Retinal and …, 2024 - Elsevier
Regulatory approval of the first two therapeutic substances for the management of
geographic atrophy (GA) secondary to age-related macular degeneration (AMD) is a major …
geographic atrophy (GA) secondary to age-related macular degeneration (AMD) is a major …
[HTML][HTML] Artificial intelligence for geographic atrophy: pearls and pitfalls
ML Enzendorfer, U Schmidt-Erfurth - Current Opinion in …, 2024 - journals.lww.com
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Oral antioxidant and lutein/zeaxanthin supplements slow geographic atrophy progression to the fovea in age-related macular degeneration
Purpose To determine whether oral micronutrient supplementation slows geographic
atrophy (GA) progression in age-related macular degeneration (AMD). Design Post hoc …
atrophy (GA) progression in age-related macular degeneration (AMD). Design Post hoc …
[HTML][HTML] Geographic atrophy segmentation using multimodal deep learning
Purpose: To examine deep learning (DL)–based methods for accurate segmentation of
geographic atrophy (GA) lesions using fundus autofluorescence (FAF) and near-infrared …
geographic atrophy (GA) lesions using fundus autofluorescence (FAF) and near-infrared …
Ophthalmology Optical Coherence Tomography Databases for Artificial Intelligence Algorithm: A Review
D Restrepo, JM Quion… - Seminars in …, 2024 - Taylor & Francis
Background Imaging plays a pivotal role in eye assessment. With the introduction of
advanced machine learning and artificial intelligence (AI), the focus has shifted to imaging …
advanced machine learning and artificial intelligence (AI), the focus has shifted to imaging …
Using Ensemble OCT-Derived Features beyond Intensity Features for Enhanced Stargardt Atrophy Prediction with Deep Learning
Featured Application This study shows promising results for the development of artificial
intelligence tools for the predicting of the progression of Stargardt disease. It further offers …
intelligence tools for the predicting of the progression of Stargardt disease. It further offers …
Combination of optical coherence tomography-derived shape and texture features are associated with development of sub-foveal geographic atrophy in dry AMD
Geographic atrophy (GA) is an advanced form of dry age-related macular degeneration
(AMD) that leads to progressive and irreversible vision loss. Identifying patients with greatest …
(AMD) that leads to progressive and irreversible vision loss. Identifying patients with greatest …
Artificial intelligence in assessing progression of age-related macular degeneration
S Frank-Publig, K Birner, S Riedl, GS Reiter… - Eye, 2024 - nature.com
The human population is steadily growing with increased life expectancy, impacting the
prevalence of age-dependent diseases, including age-related macular degeneration (AMD) …
prevalence of age-dependent diseases, including age-related macular degeneration (AMD) …
“Super‐covariates”: Using predicted control group outcome as a covariate in randomized clinical trials
B Holzhauer, ET Adewuyi - Pharmaceutical Statistics, 2023 - Wiley Online Library
The power of randomized controlled clinical trials to demonstrate the efficacy of a drug
compared with a control group depends not just on how efficacious the drug is, but also on …
compared with a control group depends not just on how efficacious the drug is, but also on …
Identifying geographic atrophy
L Clevenger, A Rachitskaya - Current Opinion in Ophthalmology, 2023 - journals.lww.com
Identification of GA and of risk factors for GA development or progression is essential when
counseling AMD patients and discussing prognosis. With new therapies on the horizon for …
counseling AMD patients and discussing prognosis. With new therapies on the horizon for …