Photocatalysis in the life science industry

L Candish, KD Collins, GC Cook, JJ Douglas… - Chemical …, 2021 - ACS Publications
In the pursuit of new pharmaceuticals and agrochemicals, chemists in the life science
industry require access to mild and robust synthetic methodologies to systematically modify …

Active targeting schemes for nano-drug delivery systems in osteosarcoma therapeutics

P Shi, Z Cheng, K Zhao, Y Chen, A Zhang… - Journal of …, 2023 - Springer
Osteosarcoma, the most common malignant tumor of the bone, seriously influences people's
lives and increases their economic burden. Conventional chemotherapy drugs achieve …

Toward biocompatible semiconductor quantum dots: from biosynthesis and bioconjugation to biomedical application

J Zhou, Y Yang, C Zhang - Chemical reviews, 2015 - ACS Publications
The understanding of biological systems at the molecular scale is increasingly reliant on the
capability of tracking miscellaneous biomolecules and their events with improved spatial …

Targeting strategies for superparamagnetic iron oxide nanoparticles in cancer therapy

D Zhi, T Yang, J Yang, S Fu, S Zhang - Acta biomaterialia, 2020 - Elsevier
Among various nanoparticles, superparamagnetic iron oxide nanoparticles (SPIONs) have
been increasingly studied for their excellent superparamagnetism, magnetic heating …

Molecular and functional imaging in cancer-targeted therapy: current applications and future directions

JW Bai, SQ Qiu, GJ Zhang - Signal Transduction and Targeted Therapy, 2023 - nature.com
Targeted anticancer drugs block cancer cell growth by interfering with specific signaling
pathways vital to carcinogenesis and tumor growth rather than harming all rapidly dividing …

Rapid Biomolecular Trifluoromethylation Using Cationic Aromatic Sulfonate Esters as Visible-Light-Triggered Radical Photocages

NJ Kuehl, MT Taylor - Journal of the American Chemical Society, 2023 - ACS Publications
Described here is a photodecaging approach to radical trifluoromethylation of biomolecules.
This was accomplished by designing a quinolinium sulfonate ester that, upon absorption of …

Emerging albumin-binding anticancer drugs for tumor-targeted drug delivery: current understandings and clinical translation

H Cho, SI Jeon, CH Ahn, MK Shim, K Kim - Pharmaceutics, 2022 - mdpi.com
Albumin has shown remarkable promise as a natural drug carrier by improving
pharmacokinetic (PK) profiles of anticancer drugs for tumor-targeted delivery. The …

In vivo targeted delivery of nanoparticles for theranosis

H Koo, MS Huh, IC Sun, SH Yuk, K Choi… - Accounts of chemical …, 2011 - ACS Publications
Therapy and diagnosis are two major categories in the clinical treatment of disease.
Recently, the word “theranosis” has been created, combining the words to describe the …

Peptide-based imaging agents for cancer detection

X Sun, Y Li, T Liu, Z Li, X Zhang, X Chen - Advanced drug delivery reviews, 2017 - Elsevier
Selective receptor-targeting peptide based agents have attracted considerable attention in
molecular imaging of tumor cells that overexpress corresponding peptide receptors due to …

Molecular imaging in the second near‐infrared window

H Wan, H Du, F Wang, H Dai - Advanced functional materials, 2019 - Wiley Online Library
In the past decade, noticeable progress has been achieved regarding fluorescence imaging
in the second near‐infrared (NIR‐II) window. Fluorescence imaging in the NIR‐II window …