Recent advances in chitosan-based layer-by-layer biomaterials and their biomedical applications

B Hu, Y Guo, H Li, X Liu, Y Fu, F Ding - Carbohydrate Polymers, 2021 - Elsevier
In recent years, chitosan-based biomaterials have been continually and extensively
researched by using layer-by-layer (LBL) assembly, due to their potentials in biomedicine …

[HTML][HTML] Chitosan nanocarriers: pioneering encapsulation and targeted delivery of 5-fluorouracil-A comprehensive review

M Rajaei, H Rashedi, F Yazdian, M Pourmadadi… - European Journal of …, 2024 - Elsevier
Fluorouracil (5FU) is a common chemotherapy drug for various cancers. It has exhibited
large potentials for the treatment of both malignant and premalignant tumors. In the …

Application of chitosan/alginate nanoparticle in oral drug delivery systems: prospects and challenges

S Li, H Zhang, K Chen, M **, SH Vu, S Jung, N He… - Drug …, 2022 - Taylor & Francis
Oral drug delivery systems (ODDSs) have various advantages of simple operation and few
side effects. ODDSs are highly desirable for colon-targeted therapy (eg ulcerative colitis and …

Nanoarchitectonics beyond perfect order–not quite perfect but quite useful

L Cao, Y Huang, B Parakhonskiy, AG Skirtach - Nanoscale, 2022 - pubs.rsc.org
Nanoarchitectonics, like architectonics, allows the design and building of structures, but at
the nanoscale. Unlike those in architectonics, and even macro-, micro-, and atomic-scale …

Harnessing the dual role of polysaccharides in treating gastrointestinal diseases: As therapeutics and polymers for drug delivery

L Corrie, M Gulati, A Awasthi, S Vishwas, J Kaur… - Chemico-Biological …, 2022 - Elsevier
Polysaccharides (PS) represent a broad class of polymer-based compounds that have been
extensively researched as therapeutics and excipients for drug delivery. As pharmaceutical …

Recent research advances on oral colon-specific delivery system of nature bioactive components: A review

S Zhao, Y Zhao, X Yang, T Zhao - Food Research International, 2023 - Elsevier
Oral colon-specific delivery system (OCDS) is a targeted approach that aims to directly
deliver bioactive compounds directly to the colon following oral administration, thereby …

Functionalized LbL film for localized delivery of STAT3 siRNA and oxaliplatin combination to treat colon cancer

LSL Janardhanam, SP Bandi… - ACS Applied Materials & …, 2022 - ACS Publications
The aim of the study was to develop and evaluate the efficacy of a functionalized layer-by-
layer (LbL) assembled film entrapped with oxaliplatin (OX) and signal transducer and …

Release studies of the anticancer drug 5-fluorouracil from chitosan-banana peel extract films

D Radha, JS Lal, KS Devaky - International Journal of Biological …, 2024 - Elsevier
F-lourouracil is an anticancer drug used for the treatment of different types of cancers. 5-
flourouracil loaded chitosan-banana peel extract films were prepared for the in vitro drug …

Glycan-based scaffolds and nanoparticles as drug delivery system in cancer therapy

H Qin, Y Teng, R Dai, A Wang, J Liu - Frontiers in Immunology, 2024 - frontiersin.org
Glycan-based scaffolds are unique in their high specificity, versatility, low immunogenicity,
and ability to mimic natural carbohydrates, making them attractive candidates for use in …

The development of a novel oral 5-Fluorouracil in-situ gelling nanosuspension to potentiate the anticancer activity against colorectal cancer cells

S Abdullah, S El Hadad, A Aldahlawi - International Journal of …, 2022 - Elsevier
Fluorouracil is an anticancer drug with a short biological half-life. This study aimed to
develop oral sustained-release nano-formulations of 5-Fluorouracil. 5-Fluorouracil …