Iron oxide nanoparticles for biomedical applications: a perspective on synthesis, drugs, antimicrobial activity, and toxicity

LS Arias, JP Pessan, APM Vieira, TMT Lima… - Antibiotics, 2018 - mdpi.com
Medical applications and biotechnological advances, including magnetic resonance
imaging, cell separation and detection, tissue repair, magnetic hyperthermia and drug …

[HTML][HTML] Magnetic iron oxide nanoparticles for imaging, targeting and treatment of primary and metastatic tumors of the brain

LL Israel, A Galstyan, E Holler, JY Ljubimova - Journal of Controlled …, 2020 - Elsevier
Magnetic nanoparticles in general, and iron oxide nanoparticles in particular, have been
studied extensively during the past 20 years for numerous biomedical applications. The …

Magnetic hyperthermia therapy for the treatment of glioblastoma: a review of the therapy's history, efficacy and application in humans

K Mahmoudi, A Bouras, D Bozec, R Ivkov… - International Journal …, 2018 - Taylor & Francis
Hyperthermia therapy (HT) is the exposure of a region of the body to elevated temperatures
to achieve a therapeutic effect. HT anticancer properties and its potential as a cancer …

EGFR targeting for cancer therapy: Pharmacology and immunoconjugates with drugs and nanoparticles

E da Silva Santos, KAB Nogueira… - International journal of …, 2021 - Elsevier
The epidermal growth factor receptor (EGFR) belongs to the tyrosine kinase receptors family
and is present in the epithelial cell membrane. Its endogenous activation occurs through the …

Systemic brain tumor delivery of synthetic protein nanoparticles for glioblastoma therapy

JV Gregory, P Kadiyala, R Doherty, M Cadena… - Nature …, 2020 - nature.com
Glioblastoma (GBM), the most aggressive form of brain cancer, has witnessed very little
clinical progress over the last decades, in part, due to the absence of effective drug delivery …

Key for crossing the BBB with nanoparticles: The rational design

SM Lombardo, M Schneider, AE Türeli… - Beilstein journal of …, 2020 - beilstein-journals.org
Central nervous system diseases are a heavy burden on society and health care systems.
Hence, the delivery of drugs to the brain has gained more and more interest. The brain is …

Drug delivery challenges and future of chemotherapeutic nanomedicine for glioblastoma treatment

LP Ganipineni, F Danhier, V Préat - Journal of controlled release, 2018 - Elsevier
Glioblastoma (GBM) is one of the most aggressive and deadliest central nervous system
tumors, and the current standard treatment is surgery followed by radiotherapy with …

Nanotechnology and nanocarrier-based drug delivery as the potential therapeutic strategy for glioblastoma multiforme: An update

JF Hsu, SM Chu, CC Liao, CJ Wang, YS Wang, MY Lai… - Cancers, 2021 - mdpi.com
Simple Summary Glioblastoma multiforme (GBM) are among the most lethal tumors. The
highly invasive nature and presence of GBM stem cells, as well as the blood brain barrier …

Convection-enhanced delivery in glioblastoma: a review of preclinical and clinical studies

A Jahangiri, AT Chin, PM Flanigan, R Chen… - Journal of …, 2017 - thejns.org
Glioblastoma is the most common malignant brain tumor, and it carries an extremely poor
prognosis. Attempts to develop targeted therapies have been hindered because the blood …

Hyperthermia treatment advances for brain tumors

GP Skandalakis, DR Rivera, CD Rizea… - International Journal …, 2020 - Taylor & Francis
Hyperthermia therapy (HT) of cancer is a well-known treatment approach. With the advent of
new technologies, HT approaches are now important for the treatment of brain tumors. We …