The problem of antibiotic resistance is on the rise, with multidrug-resistant strains emerging
even to the last resort antibiotics. The drug discovery process is often stalled by stringent cut …

Antimicrobial resistance has been a global health challenge that threatens our ability to
control and treat life-threatening bacterial infections. Despite ongoing efforts to identify new …

The increasing emergence and dissemination of multidrug resistant (MDR) bacterial
pathogens accelerate the desires for new antibiotics. Natural products dominate the …

Antibiotic tolerance, the ability of a typically susceptible microorganism to survive extended
periods of exposure to antibiotics, has a critical role in chronic and recurrent bacterial …

New approaches to target antibacterial agents toward Gram-negative bacteria are key, given
the rise of antibiotic resistance. Since the discovery of polymyxin B nonapeptide as a potent …

The potentiation of antibiotics is a promising strategy for combatting antibiotic-
resistant/tolerant bacteria. Herein, we report that a 5-min sublethal heat shock enhances the …

Because of the rise in antibiotic resistance and the dwindling pipeline of effective antibiotics,
it is imperative to explore avenues that breathe new life into existing drugs. This is …

The self‐preservation and intelligent survival abilities of methicillin‐resistant Staphylococcus
aureus (MRSA) result in the ineffective treatment of many antibiotics. Nano‐drug delivery …

Persistent generation of tetracycline (TC) resistant bacteria poses serious risks for public
health. It is of great importance to develop a strategy for rapid screening TC adjuvants for …

The rapid emergence and spread of multidrug-resistant bacterial pathogens require the
development of antibacterial agents that are robustly effective while inducing no toxicity or …