Nucleic acids‐based next generation biopharmaceuticals (ie, pDNA, oligonucleotides, short
interfering RNA) are potential pioneering materials to cope with various incurable diseases …

The polyplexes which are formed between cationic polymers and DNA through electrostatic
interactions and thus known as polycation/DNA complexes, are by far the most widely used …

Numerous studies have examined how the cellular delivery of gold nanoparticles (AuNPs) is
influenced by different physical and chemical characteristics; however, the complex …

Carbon nanotubes (CNTs) consist of carbon atoms arranged in sheets of graphene rolled up
into cylindrical shapes. This class of nanomaterials has attracted attention because of their …

Gemini surfactants are versatile gene delivery agents because of their ability to bind and
compact DNA and their low cellular toxicity. Through modification of the alkyl tail length and …

Recent progress in nanotechnology has triggered the site specific drug/gene delivery
research and gained wide acknowledgment in contemporary DNA therapeutics. Amongst …

Linear polyethylenimine (lPEI, 25 kDa) nanoparticles'(LPN) series was synthesized by
varying percentage of cross-linking with 1, 4-butanediol diglycidyl ether (BDE) and their size …

A chief objective of gene transportation studies is to manipulate clinically accepted carriers
that can be utilized to combat incurable diseases. Despite various strategies, efficiency and …

The purpose of the present study is to provide a tool for an efficient design and synthesis of
non-viral vectors for small RNA delivery. The effects of properties of the polycation, such as …

Delivery of DNA and siRNA into mammalian cells is a powerful technique in treating various
diseases caused by single gene defects. Herein, we report a highly efficient delivery system …