Primary aldosteronism—a multidimensional syndrome

AF Turcu, J Yang, A Vaidya - Nature Reviews Endocrinology, 2022 - nature.com
Primary aldosteronism is a common cause of hypertension and is a risk factor for
cardiovascular and renal morbidity and mortality, via mechanisms mediated by both …

Primary aldosteronism: state-of-the-art review

A Vaidya, GL Hundemer, K Nanba… - American Journal of …, 2022 - academic.oup.com
We are witnessing a revolution in our understanding of primary aldosteronism (PA). In the
past 2 decades, we have learned that PA is a highly prevalent syndrome that is largely …

[11C]metomidate PET-CT versus adrenal vein sampling for diagnosing surgically curable primary aldosteronism: a prospective, within-patient trial

X Wu, R Senanayake, E Goodchild, WA Bashari… - Nature Medicine, 2023 - nature.com
Primary aldosteronism (PA) due to a unilateral aldosterone-producing adenoma is a
common cause of hypertension. This can be cured, or greatly improved, by adrenal surgery …

Treating primary aldosteronism-induced hypertension: novel approaches and future outlooks

N Mullen, J Curneen, PT Donlon, P Prakash… - Endocrine …, 2024 - academic.oup.com
Primary aldosteronism (PA) is the most common cause of secondary hypertension and is
associated with increased morbidity and mortality when compared with blood pressure …

Mineralocorticoid receptor signalling in primary aldosteronism

J Yang, MJ Young, TJ Cole… - Journal of …, 2023 - joe.bioscientifica.com
Primary aldosteronism, or Conn syndrome, is the most common endocrine cause of
hypertension. It is associated with a higher risk of cardiovascular, metabolic and renal …

Aldosterone, renin, and aldosterone-to-renin ratio variability in screening for primary aldosteronism

E Ng, SM Gwini, R Libianto, KW Choy… - The Journal of …, 2023 - academic.oup.com
Context The plasma aldosterone concentration (PAC), renin, and aldosterone-to-renin ratio
(ARR) are used to screen for primary aldosteronism (PA). Substantial intra-individual …

Performance of aldosterone-to-renin ratio before washout of antihypertensive drugs in screening of primary aldosteronism

X Liu, S Hao, J Bian, Y Lou, H Zhang… - The Journal of …, 2024 - academic.oup.com
Objective The aim of this study is to evaluate performance of aldosterone-to-renin ratio
(ARR) before washout of antihypertensive drugs as a screening test for primary …

[HTML][HTML] 2023 Korean endocrine society consensus guidelines for the diagnosis and management of primary aldosteronism

J Ha, JH Park, KJ Kim, JH Kim… - Endocrinology and …, 2023 - synapse.koreamed.org
Primary aldosteronism (PA) is a common, yet underdiagnosed cause of secondary
hypertension. It is characterized by an overproduction of aldosterone, leading to …

Global and regional prevalence and cardiovascular risk of primary aldosteronism: A systematic review and meta-analysis

M Huang, J Li, X Zhao, R Fu, X Li, W Jiang - Current Problems in …, 2024 - Elsevier
Background An updated understanding of global prevalence of primary aldosteronism (PA)
is essential for the development of primary prevention and management strategies for PA …

Prevalence and characteristics of low-renin hypertension in a primary care population

SS Shah, R Libianto, SM Gwini, G Rusell… - Journal of the …, 2024 - academic.oup.com
Introduction Low-renin hypertension is an underrecognized subtype of hypertension with
specific treatment options. This study aims to identify the prevalence in primary care and to …