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The essential role of tick salivary glands and saliva in tick feeding and pathogen transmission
As long-term pool feeders, ticks have developed myriad strategies to remain discreetly but
solidly attached to their hosts for the duration of their blood meal. The critical biological …
solidly attached to their hosts for the duration of their blood meal. The critical biological …
Tick salivary compounds: their role in modulation of host defences and pathogen transmission
Ticks require blood meal to complete development and reproduction. Multifunctional tick
salivary glands play a pivotal role in tick feeding and transmission of pathogens. Tick …
salivary glands play a pivotal role in tick feeding and transmission of pathogens. Tick …
Complement evasion by human pathogens
The human immune system has developed an elaborate network of cascades for dealing
with microbial intruders. Owing to its ability to rapidly recognize and eliminate …
with microbial intruders. Owing to its ability to rapidly recognize and eliminate …
The role of saliva in tick feeding
When attempting to feed on their hosts, ticks face the problem of host hemostasis (the
vertebrate mechanisms that prevent blood loss), inflammation (that can produce itching or …
vertebrate mechanisms that prevent blood loss), inflammation (that can produce itching or …
Ticks and tick-borne pathogens at the cutaneous interface: host defenses, tick countermeasures, and a suitable environment for pathogen establishment
S Wikel - Frontiers in microbiology, 2013 - frontiersin.org
Ticks are unique among hematophagous arthropods by continuous attachment to host skin
and blood feeding for days; complexity and diversity of biologically active molecules …
and blood feeding for days; complexity and diversity of biologically active molecules …
The pathogenesis of lyme neuroborreliosis: from infection to inflammation
This review describes the current knowledge of the pathogenesis of acute Lyme
neuroborreliosis (LNB), from invasion to inflammation of the central nervous system. Borrelia …
neuroborreliosis (LNB), from invasion to inflammation of the central nervous system. Borrelia …
Implication of haematophagous arthropod salivary proteins in host-vector interactions
A Fontaine, I Diouf, N Bakkali, D Missé, F Pagès… - Parasites & vectors, 2011 - Springer
The saliva of haematophagous arthropods contains an array of anti-haemostatic, anti-
inflammatory and immunomodulatory molecules that contribute to the success of the blood …
inflammatory and immunomodulatory molecules that contribute to the success of the blood …
Complement evasion of pathogens: common strategies are shared by diverse organisms
PF Zipfel, R Würzner, C Skerka - Molecular immunology, 2007 - Elsevier
Infectious diseases represent a major health problem. Based on the limited efficacy of
existing drugs and vaccines and the increasing antibiotic resistance new strategies are …
existing drugs and vaccines and the increasing antibiotic resistance new strategies are …
TickSialoFam (TSFam): a database that helps to classify tick salivary proteins, a review on tick salivary protein function and evolution, with considerations on the tick …
Tick saliva contains a complex mixture of peptides and non-peptides that counteract their
hosts' hemostasis, immunity, and tissue-repair reactions. Recent transcriptomic studies have …
hosts' hemostasis, immunity, and tissue-repair reactions. Recent transcriptomic studies have …
Sialome diversity of ticks revealed by RNAseq of single tick salivary glands
Ticks salivate while feeding on their hosts. Saliva helps blood feeding through host anti-
hemostatic and immunomodulatory components. Previous transcriptomic and proteomic …
hemostatic and immunomodulatory components. Previous transcriptomic and proteomic …