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Evolution of the SARS-CoV-2 Omicron spike
RJ Parsons, P Acharya - Cell reports, 2023 - cell.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of
concern, first identified in November 2021, rapidly spread worldwide and diversified into …
concern, first identified in November 2021, rapidly spread worldwide and diversified into …
Mechanical communication within the microtubule through network-based analysis of tubulin dynamics
The identification of the mechanisms underlying the transfer of mechanical vibrations in
protein complexes is crucial to understand how these super-assemblies are stabilized to …
protein complexes is crucial to understand how these super-assemblies are stabilized to …
Exploring TAS2R46 biomechanics through molecular dynamics and network analysis
Understanding the intricate interplay between structural features and signal-processing
events is crucial for unravelling the mechanisms of biomolecular systems. G protein-coupled …
events is crucial for unravelling the mechanisms of biomolecular systems. G protein-coupled …
Evolutionary rewiring of the dynamic network underpinning allosteric epistasis in NS1 of the influenza A virus
Viral proteins frequently mutate to evade host innate immune responses, yet the impact of
these mutations on the molecular energy landscape remains unclear. Epistasis, the …
these mutations on the molecular energy landscape remains unclear. Epistasis, the …
Multiscale Computational Analysis of the Effect of Taxol on Microtubule Mechanics
Microtubules (MTs) are widely recognized as targets for cancer therapies. They are directly
related to unique mechanical properties, closely dependent on MT architecture and tubulin …
related to unique mechanical properties, closely dependent on MT architecture and tubulin …
Complementary Pocket and Network-Based Approach to Search for Spike Protein Allosteric Pocket Sites
COVID-19 is a persistent public health concern due to the emergence of more virulent and
contagious variants resulting from mutations in the spike protein. The spike protein in newer …
contagious variants resulting from mutations in the spike protein. The spike protein in newer …
Predicting permeation of compounds across the outer membrane of P. aeruginosa using molecular descriptors
The ability Gram-negative pathogens have at adapting and protecting themselves against
antibiotics has increasingly become a public health threat. Data-driven models identifying …
antibiotics has increasingly become a public health threat. Data-driven models identifying …
Molecular Biomechanics of the TAS2R46 Bitter Taste Receptor through Network-based Investigation
The intricate relationship between structural characteristics and the resultant signal-
processing events is fundamental in comprehending the functions and mechanisms inherent …
processing events is fundamental in comprehending the functions and mechanisms inherent …
Paired associated SARS-CoV-2 spike variable positions: a network analysis approach to emerging variants
Y Manoussopoulos, C Anastassopoulou… - Msystems, 2023 - journals.asm.org
Amino acids in variable positions of proteins may be correlated, with potential structural and
functional implications. Here, we apply exact tests of independence in R× C contingency …
functional implications. Here, we apply exact tests of independence in R× C contingency …