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Engineering cells for precision drug delivery: new advances, clinical translation, and emerging strategies
Cells have emerged as a promising new form of drug delivery carriers owing to their
distinguished advantages such as naturally bypassing immune recognition, intrinsic …
distinguished advantages such as naturally bypassing immune recognition, intrinsic …
Fate map** of Spp1 expression reveals age-dependent plasticity of disease-associated microglia-like cells after brain injury
Y Lan, X Zhang, S Liu, C Guo, Y **, H Li, L Wang… - Immunity, 2024 - cell.com
Microglial reactivity to injury and disease is emerging as a heterogeneous, dynamic, and
crucial determinant in neurological disorders. However, the plasticity and fate of disease …
crucial determinant in neurological disorders. However, the plasticity and fate of disease …
Translating animal models of ischemic stroke to the human condition
AV Matur, E Candelario-Jalil, S Paul… - Translational Stroke …, 2023 - Springer
Ischemic stroke is a leading cause of death and disability. However, very few
neuroprotective agents have shown promise for treatment of ischemic stroke in clinical trials …
neuroprotective agents have shown promise for treatment of ischemic stroke in clinical trials …
Erythrocyte–brain endothelial interactions induce microglial responses and cerebral microhemorrhages in vivo
Background Cerebral microhemorrhages (CMH) are associated with stroke, cognitive
decline, and normal aging. Our previous study shows that the interaction between …
decline, and normal aging. Our previous study shows that the interaction between …
A minimally invasive thrombotic stroke model to study circadian rhythm in awake mice
Experimental stroke models in rodents are essential for mechanistic studies and therapeutic
development. However, these models have several limitations negatively impacting their …
development. However, these models have several limitations negatively impacting their …
Modeling distal middle cerebral artery occlusion in neonatal rodents with magnetic nanoparticles or magnetized red blood cells
JM Jia, Y ** - Neural Repair: Methods and Protocols, 2023 - Springer
It is challenging to establish animal models to mimic perinatal arterial ischemic stroke. Here,
we provided two approaches that precisely occlude rodent pups' distal middle cerebral …
we provided two approaches that precisely occlude rodent pups' distal middle cerebral …
Neurovascular Coupling is Required for Amygdala Neuronal Activation and Associated Emotional Behaviors in Mice, Depending on NMDA Receptor Subunit 2D …
J Ruan, Y Zhang, D Zhang, H **e, X Quan, W Wang… - bioRxiv, 2023 - biorxiv.org
Proper cerebral function depends on intact neurovascular coupling (NVC), a conservative
biological process in mammals that can effectively and spatiotemporally regulate cerebral …
biological process in mammals that can effectively and spatiotemporally regulate cerebral …
A Novel Magnetic Particle Model of Ischemic Stroke in Vivo
KS Marks - 2023 - search.proquest.com
Stroke is a leading cause of death and disability worldwide, with a stroke occurring every 40
seconds in the United States alone. Of these, nearly 90% are due to ischemic stroke where …
seconds in the United States alone. Of these, nearly 90% are due to ischemic stroke where …
or Magnetized Red Blood Cells
JM Jia, Y ** - Neural Repair: Methods and Protocols, 2023 - books.google.com
It is challenging to establish animal models to mimic perinatal arterial ischemic stroke. Here,
we provided two approaches that precisely occlude rodent pups' distal middle cerebral …
we provided two approaches that precisely occlude rodent pups' distal middle cerebral …