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Has ferrocene really delivered its role in accentuating the bioactivity of organic scaffolds?
Ferrocene is an important structural core in bioorganometallic chemistry because of its
inherent stability, excellent redox properties, and low toxicity. Ferroquine and ferrocifen are …
inherent stability, excellent redox properties, and low toxicity. Ferroquine and ferrocifen are …
Ferrocene derivatives as anti-infective agents
BS Ludwig, JDG Correia, FE Kühn - Coordination Chemistry Reviews, 2019 - Elsevier
Infectious diseases like malaria, tuberculosis or HIV are among the leading causes of death
worldwide according to WHO estimations. Nevertheless, the fight against infectious diseases …
worldwide according to WHO estimations. Nevertheless, the fight against infectious diseases …
Perspectives of medicinally privileged chalcone based metal coordination compounds for biomedical applications
Recent clinical reports have highlighted the increasing occurrence of drug resistance of
known therapeutics. Particularly, antibiotic resistant microorganisms and multidrug …
known therapeutics. Particularly, antibiotic resistant microorganisms and multidrug …
Ferrocene conjugates of chloroquine and other antimalarials: the development of ferroquine, a new antimalarial
D Dive, C Biot - ChemMedChem, 2007 - pmc.ncbi.nlm.nih.gov
A convenient approach to antimalarial drug discovery is the use of the organic scaffold of a
known antimalarial drug and an organometallic moiety to alter its unwanted properties …
known antimalarial drug and an organometallic moiety to alter its unwanted properties …
Metalloantimalarials
PF Salas, C Herrmann, C Orvig - Chemical reviews, 2013 - ACS Publications
Malaria is a worldwide neglected infectious disease that, despite decades of research
invested in its prevention and treatment, remains one of the main causes of mortality and …
invested in its prevention and treatment, remains one of the main causes of mortality and …
α-Alkylation of ketones with primary alcohols catalyzed by a Cp* Ir complex bearing a functional bipyridonate ligand
F Li, J Ma, N Wang - The Journal of Organic Chemistry, 2014 - ACS Publications
A Cp* Ir complex bearing a functional bipyridonate ligand was found to be a highly effective
and versatile catalyst for the α-alkylation of ketones with primary alcohols under extremely …
and versatile catalyst for the α-alkylation of ketones with primary alcohols under extremely …
Synthesis of new chalcone derivatives containing acridinyl moiety with potential antimalarial activity
V Tomar, G Bhattacharjee, S Rajakumar… - European journal of …, 2010 - Elsevier
A series of novel chalcones bearing acridine moiety attached to the amino group in their ring
A have been synthesized through noncatalyzed nucleophilic aromatic substitution reaction …
A have been synthesized through noncatalyzed nucleophilic aromatic substitution reaction …
Synthesis of a-Alkylated Ketones via Tandem Acceptorless Dehydrogenation/a-Alkylation from Secondary and Primary Alcohols Catalyzed by Metal–Ligand Bifunctional Iridium …
R Wang, J Ma, F Li - The Journal of Organic Chemistry, 2015 - ACS Publications
A new strategy for the synthesis of α-alkylated ketones via tandem acceptorless
dehydrogenation/α-alkylation from secondary and primary alcohols was proposed and …
dehydrogenation/α-alkylation from secondary and primary alcohols was proposed and …
Ferrocene functionalized endocrine modulators as anticancer agents
We present here some of our studies on the synthesis and behaviour of ferrocenyl selective
endocrine receptor modulators against cancer cells, particularly breast and prostate …
endocrine receptor modulators against cancer cells, particularly breast and prostate …
1H-1, 2, 3-triazole tethered isatin-ferrocene conjugates: Synthesis and in vitro antimalarial evaluation
Abstract 1H-1, 2, 3-triazole tethered isatin-ferrocene conjugates were synthesized and
evaluated for their antiplasmodial activities against chloroquine-susceptible (3D7) and …
evaluated for their antiplasmodial activities against chloroquine-susceptible (3D7) and …