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[HTML][HTML] Recent technical developments and clinical research applications of sodium (23Na) MRI
Sodium is an essential ion that plays a central role in many physiological processes
including the transmembrane electrochemical gradient and the maintenance of the body's …
including the transmembrane electrochemical gradient and the maintenance of the body's …
SCN5A channelopathy: arrhythmia, cardiomyopathy, epilepsy and beyond
Influx of sodium ions through voltage-gated sodium channels in cardiomyocytes is essential
for proper electrical conduction within the heart. Both acquired conditions associated with …
for proper electrical conduction within the heart. Both acquired conditions associated with …
Precise starving therapy via physiologically dependent photothermal conversion promoted mitochondrial calcification based on multi‐functional gold nanoparticles for …
X Chang, X Tang, J Liu, Z Zhu, W Mu… - Advanced Functional …, 2023 - Wiley Online Library
Starving therapy based on tumor calcification has been considered as a promising strategy
with high biosafety for tumor treatment. However, the limited calcium (Ca2+) concentration …
with high biosafety for tumor treatment. However, the limited calcium (Ca2+) concentration …
Bioelectric pharmacology of cancer: a systematic review of ion channel drugs affecting the cancer phenotype
Cancer is a pernicious and pressing medical problem; moreover, it is a failure of
multicellular morphogenesis that sheds much light on evolutionary developmental biology …
multicellular morphogenesis that sheds much light on evolutionary developmental biology …
Sodium channels and the ionic microenvironment of breast tumours
Cancers of epithelial origin such as breast, prostate, cervical, gastric, colon and lung cancer
account for a large proportion of deaths worldwide. Better treatment of metastasis, the main …
account for a large proportion of deaths worldwide. Better treatment of metastasis, the main …
Voltage-gated sodium channels: from roles and mechanisms in the metastatic cell behavior to clinical potential as therapeutic targets
During the second half of the last century, the prevalent knowledge recognized the voltage-
gated sodium channels (VGSCs) as the proteins responsible for the generation and …
gated sodium channels (VGSCs) as the proteins responsible for the generation and …
Disrupting Na+ ion homeostasis and Na+/K+ ATPase activity in breast cancer cells directly modulates glycolysis in vitro and in vivo
Background Glycolytic flux is regulated by the energy demands of the cell. Upregulated
glycolysis in cancer cells may therefore result from increased demand for adenosine …
glycolysis in cancer cells may therefore result from increased demand for adenosine …
Chronic high-salt diet activates tumor-initiating stem cells leading to breast cancer proliferation
Several chronic inflammatory diseases have been linked to high-salt (HS) diets. Chronic
inflammation is an established causative hallmark of cancer. However, a direct role of HS …
inflammation is an established causative hallmark of cancer. However, a direct role of HS …
A bioinformatics analysis: ZFHX4 is associated with metastasis and poor survival in ovarian cancer
S Zong, P Xu, Y Xu, Y Guo - Journal of Ovarian Research, 2022 - Springer
Background Metastasis was the major cause of the high mortality in ovarian cancer.
Although some mechanisms of metastasis in ovarian cancer were proposed, few have been …
Although some mechanisms of metastasis in ovarian cancer were proposed, few have been …
Metal Ion Signaling in Biomedicine
Complex multicellular organisms are composed of distinct tissues involving specialized cells
that can perform specific functions, making such life forms possible. Species are defined by …
that can perform specific functions, making such life forms possible. Species are defined by …