Long non-coding RNA: Classification, biogenesis and functions in blood cells
While there exist some long non-coding RNAs (lncRNAs) that are structurally similar to
mRNAs (capped, spliced, poly a tail), not all of the lncRNAs exhibit these features …
mRNAs (capped, spliced, poly a tail), not all of the lncRNAs exhibit these features …
Long non-coding RNAs in cancer: implications for diagnosis, prognosis, and therapy
Y Qian, L Shi, Z Luo - Frontiers in medicine, 2020 - frontiersin.org
Long non-coding RNAs (lncRNAs) are major components of cellular transcripts that are
arising as important players in various biological pathways. They have received extensive …
arising as important players in various biological pathways. They have received extensive …
Technological developments in lncRNA biology
S Jathar, V Kumar, J Srivastava, V Tripathi - Long Non Coding RNA …, 2017 - Springer
It is estimated that more than 90% of the mammalian genome is transcribed as non-coding
RNAs. Recent evidences have established that these non-coding transcripts are not junk or …
RNAs. Recent evidences have established that these non-coding transcripts are not junk or …
LncRNA: a link between RNA and cancer
G Yang, X Lu, L Yuan - Biochimica et Biophysica Acta (BBA)-Gene …, 2014 - Elsevier
Unraveling the gene expression networks governing cancer initiation and development is
essential while remains largely uncompleted. With the innovations in RNA-seq technologies …
essential while remains largely uncompleted. With the innovations in RNA-seq technologies …
CPAT: Coding-Potential Assessment Tool using an alignment-free logistic regression model
Thousands of novel transcripts have been identified using deep transcriptome sequencing.
This discovery of large and 'hidden'transcriptome rejuvenates the demand for methods that …
This discovery of large and 'hidden'transcriptome rejuvenates the demand for methods that …
On the classification of long non-coding RNAs
Long non-coding RNAs (lncRNAs) have been found to perform various functions in a wide
variety of important biological processes. To make easier interpretation of lncRNA …
variety of important biological processes. To make easier interpretation of lncRNA …
Molecular mechanisms of long noncoding RNAs
KC Wang, HY Chang - Molecular cell, 2011 - cell.com
Long noncoding RNAs (lncRNAs) are an important class of pervasive genes involved in a
variety of biological functions. Here we discuss the emerging archetypes of molecular …
variety of biological functions. Here we discuss the emerging archetypes of molecular …
Genome regulation by long noncoding RNAs
The central dogma of gene expression is that DNA is transcribed into messenger RNAs,
which in turn serve as the template for protein synthesis. The discovery of extensive …
which in turn serve as the template for protein synthesis. The discovery of extensive …
Epigenetic regulation by long noncoding RNAs
JT Lee - Science, 2012 - science.org
Recent studies show that transcription of the mammalian genome is not only pervasive but
also enormously complex. It is estimated that an average of 10 transcription units, the vast …
also enormously complex. It is estimated that an average of 10 transcription units, the vast …
Long non-coding RNAs are emerging targets of phytochemicals for cancer and other chronic diseases
The long non-coding RNAs (lncRNAs) are the crucial regulators of human chronic diseases.
Therefore, approaches such as antisense oligonucleotides, RNAi technology, and small …
Therefore, approaches such as antisense oligonucleotides, RNAi technology, and small …